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BIOCHEMISTRY - 1st Year 1st Sem Comprehensive Exam > MIDTERMS 2ND EVALS (2022) > Flashcards

MIDTERMS 2ND EVALS (2022) Flashcards

1
Q

Effect of Nitroglycerin

A

Smooth Muscle RELAXATION

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2
Q

Basement membrane-

A

LAMININ

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3
Q

It is the hormone that stimulates adenylyl cyclase

A

ADH

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4
Q

Repeating motifs (I, II, III) and Arg-Gly-Asp (RDG) sequence

A

FIBRONECTIN

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5
Q

Scurvy enzyme deficiency

A

lysyl hydroxylase

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6
Q

3 distinct elongated polypeptide chains of A, B1, B2

A

LAMININ

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7
Q

All GAGs contain sulfate group except –

A

HYALURONIC ACID

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8
Q

Group I hormones

A

LONG ACTING

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9
Q

Cornea

A

KERATAN SUFATE I

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10
Q

Calmoldulin

A

4 CALCIUM

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11
Q

Group 2 hormones

A

RAPID ONSET

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12
Q

Achondroplasia characteristics except

A

MICROCEPHALY

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13
Q

First discovered secondary messenger

A

cAMP

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14
Q

Jak/stat pathway

A

GROWTH HORMONES

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15
Q

Glucocorticoids

A

HEATH SHOCK PROTEIN 90

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16
Q

IP3:

A

ENDOPLASMIC RETICULUM

17
Q

True of elastin except

A

HAS 19 TYPES

18
Q

Same between skeletal and cardiac except?
a. both straited
b. actin-myosin-tropomyosin-troponin system
Answere: c.dependent on extracellular ca++ /

A

Answere: c.dependent on extracellular ca++ /

19
Q

Cilia and flagella

A

MICROTUBULE

20
Q

causes DISSOCIATION of the COREREPRESSOR upon bind to the

receptor.

A

Thyroid Hormone

21
Q

modifies alpha subunit, high levels of Camp

A

cholera toxin

22
Q

lies in the I BAND

A

Thin filaments

23
Q

Happens in rigor mortis excep t-

A

NO ACTIN is released

24
Q

Precursor of collagen

A

PREPROCOLLAGEN

25
Q

Glucocorticoid receptor directly binds to p65 subunit of NF-KB and inhibits its
activation.
TRUE OR FALSE

A

TRUE

26
Q

High-energy conformation

A

ADP-Pi-Myosin Complex

27
Q

Ca2+-Na+ exchanger

A

principal ROUTE of EXIT of Ca2+ from myocytes

28
Q

Unique to striated muscle

A

TROPONIN

29
Q

Tropinin I

A

INHIBITS F-actin-myosin interaction

30
Q

smooth muscles

A

Sarcomere NOT ALIGNED

31
Q

Cytoskeleton

A

perform MECHANICAL work

32
Q

True about biosynthesis of GAG:

A

Chain Elongation occurs in the Golgi Apparatus

33
Q

highly SOLUBLE

A

ELASTIN

34
Q

Cardinal principle of the biosynthesis of collagen type 1

A

SELF-ASSEMBLY

35
Q

Source of ATP replenishment for contraction-relaxation cycle:

A
  • Glycolysis
  • Oxidative Phosphorylation
  • Creatine Phosphate
  • 2 Molecules of ADP
    Ans. EXCEPT GLUCONEOGENESIS
36
Q

True of skeletal muscle fiber type I:

A

maintain relatively SUSTAINED CONTRACTIONS

37
Q

arranged around thick filament as secondary hexagonal array

A

Thin filament-

38
Q

In collagen, aside from proline and hydroxyproline, glycosylation could also happen
to what amino acid?

A

HYDROXYLYSINE

BIOCHEMISTRY - 1st Year 1st Sem Comprehensive Exam (16 decks)

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