Pre-eclampsia Flashcards
1
Q
triad
A
hypertension
proteinuria
oedema
2
Q
pathogenesis
A
abnormal placentation and failure of trophoblast invasion cause spiral arteries to stay as high resistance/low flow vessels, leading to placental ischaemia -> endothelial damage and thrombosis
3
Q
timing of pre-eclampsia
A
beyond 20 weeks
4
Q
how does the oedema form?
A
kidney function declines so slat and water retention
5
Q
most common risk factor
A
previous pre-eclampsia
6
Q
other risk factors:
A
pre-exisitng hypertension diabetes autoimmune disease (lupus, RA) renal disease family hx of pre-eclampsia obesity
7
Q
clinical features of pre-eclampsia
A
headache, visual disturbance, RUQ pain, n and V, peripheral oedema
8
Q
what can be used to assess blood flow (and therefore pre-eclampsia)
A
MUAD
9
Q
complications:
A
eclampsia pulmonary oedema stroke foetal damage (IUGR, placental abruption, still birth) HELLP syndrome
10
Q
management
A
assess need for delivery
give anti hypertensives
Hydrocortisone (mature foetal lungs)
11
Q
cure for pre-eclampsia
A
delivery of baby!!
