Postsynaptic Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

how is Each related to Ena and Ek?

A

it is in between.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the fastest type of signal transduction motif

A

ligand-gated channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which type of block uses competitive inhibition?

A

non-depolarizing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Depolarizing Block: what chemicals, phases

A

nicotinic receptor agonists in high [ ]. Depolarize then block transmission. Phase 1-block by depolarization. Phase 2-block by desensitization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tubocurarine

A

non-depolarizing blocker, prototype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what muscles must be relaxed to intubate

A

masseter, laryngeal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what does -curonium mean? -curium?

A

steroid, benzylisoquinolinium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

pancuronium: duration, side effects, excretion

A

long duration. blocks vagal tone (tachycardia). renal excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

vecuronium: duration, side effects, excretion

A

intermediate, no CV effects, biliary excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

atracurium and cisatracurium: duration, excretion, best uses

A

intermediate, hoffman elimination, RENAL FAILURE pts. Cis has no histamine and no seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

rocuronium: popular for? elimination?

A

intubation. biliary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

succinylcholine: uses, structure, side effects, contraindication, metabolism

A

intubation, 2 ach end to end, malignant hyperthermia, burn victims (elevated serum K leads to CV collapse), plasma cholinesterases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

malignant hyperthermia: problem, treatment

A

ryantodine receptor hypersensitivity so it remains open and muscle contracts. Give Dantrolene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

dantrolene

A

given for malignant hyperthermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

excretion for most of these drugs and exceptions.

A

Kidney. vecuronium and rocuronium are BILIARY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

edrophonium: what is it, clinical use

A

short acting anti-cholinesterase, to test for MG

17
Q

when do you get synergy?

A

when agents act at two different parts of the mechanism.