Adrenergic jxn Flashcards
1
Q
Uptake one vs uptake 2
A
1: high affinity, low capacity. 2: low affinity, high capacity. 2 becomes important at wide jxns.
2
Q
Synthesis of catecholamines
A
Tyrosine to dopamine to norepinephrine to epinephrine
3
Q
what enzymes metabolize catecholamines
A
MAO or COMT
4
Q
What are two metanephrine derivatives and what are their uses
A
VMA: measures peripheral activity, test for pheochromocytoma (elevated). MHPG: measures CNS catecholaminergic activity
