Post-absorptive state

Question 1

Is pyruvate kinase involved in glycolysis or gluconeogenesis?

Answer 1

Glycolysis

Question 2

What is the role of glucose 6-phosphatase in gluconeogenesis?

Answer 2

Glucose 6-phosphatase catalyzes the final step of gluconeogenesis, converting glucose-6-phosphate into free glucose.

Question 3

What is the function of phosphoenolpyruvate carboxykinase (PEPCK) in gluconeogenesis?

Answer 3

PEPCK catalyzes the conversion of oxaloacetate to phosphoenolpyruvate, a key step in gluconeogenesis.

Question 4

Which enzyme in gluconeogenesis is responsible for converting fructose 1,6-bisphosphate to fructose 6-phosphate?

Answer 4

Fructose 1,6-bisphosphatase catalyzes the dephosphorylation of fructose 1,6-bisphosphate to fructose 6-phosphate in gluconeogenesis.

Question 5

What is the role of pyruvate carboxylase in gluconeogenesis?

Answer 5

Pyruvate carboxylase converts pyruvate into oxaloacetate, an essential step in gluconeogenesis.

Question 6

What protein is modulated by insulin to inhibit gluconeogenesis?

Answer 6

Fox01

Question 7

Biotin is a prosthetic group for enzymes catalysing…?

Answer 7

Carboxylation

Question 8

Can alanine contribute to glucose synthesis?

Answer 8

Alanine can be converted into pyruvate, which can be used to synthesise glucose through gluconeogenesis.

Question 9

What process converts pyruvate into glucose (mainly in liver)?

Answer 9

Gluconeogenesis

Question 10

Where is Glucose-6-phosphatase present?

Answer 10

Only in the liver and kidney (tissues that maintain blood glucose levels)

Question 11

Why does glycogenolysis use phosphorylation and not glycolysis?

Answer 11

Glycolysis would result in glucose, which can exit the cell