Compartmentalisation Flashcards

1
Q

How many molecules of NADH + H+ are generated in one cycle of the TCA cycle?

A

3

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2
Q

How many molecules of CO2 are released during one cycle of the TCA cycle?

A

2

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3
Q

What carries out the conversion of ADP to ATP?

A

ATP synthase

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4
Q

What is the primary role of the electron transport chain in mitochondria?

A

Generates a proton gradient across the inner mitochondrial membrane.

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5
Q

How does the electron transport chain contribute to cellular respiration?

A

Reduces oxygen to water (key step in the production of ATP)

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6
Q

What does the electron transport chain do with reducing equivalents?

A

Transfers reducing equivalents (e.g., electrons from NADH and FADH2) between complexes in the chain.

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7
Q

Which component of the electron transport chain carries only one electron at a time?

A

Cytochrome c

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8
Q

True or False: Cytochrome c oxidase carries one electron at a time.

A

False. Cytochrome c oxidase carries four electrons (it reduces oxygen to water), not just one.

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9
Q

What is the role of ubiquinone (CoQ) in the electron transport chain?

A

Carries two electrons at a time and transports electrons between Complex I/II and Complex III in the electron transport chain.

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10
Q

How many electrons does NADH-CoQ reductase carry in the electron transport chain?

A

2

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11
Q

What is the role of the alpha, beta-hexamer in ATP synthase?

A

The alpha, beta-hexamer undergoes conformational changes to facilitate the binding and synthesis of ATP during the process of proton flow.

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12
Q

True or False: Flow of protons from the intermembrane space into the mitochondrial matrix is crucial for ATP synthesis by ATP synthase.

A

True. The flow of protons through ATP synthase drives the enzyme’s function to produce ATP.

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13
Q

What process is responsible for driving the rotation of the gamma-subunit in ATP synthase?

A

The flow of protons through ATP synthase drives the rotation of the gamma-subunit

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13
Q

What does the rotation of the c-subunit ring in ATP synthase contribute to?

A

Contributes to the proton gradient used for driving ATP synthesis in ATP synthase.

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14
Q

Why does the movement of electrons from glucose to oxygen release energy?

A

Oxygen has a higher redox potential than glucose

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