Porcine Circovirus Type 2 Associated Disease (PCVAD)

Question 1

Etiology

Answer 1

Porcine circovirus type 2 (PCV2)

Question 2

PCV2 emerged as a swine pathogen of significance in the late 19___’s.

Answer 2

1990s

Question 3

PCVAD was formerly known as:

Answer 3

Post-weaning multisystemic wasting syndrome (PMWS)

Question 4

Clinically affected herds often see nursery mortality between ____ and ____ %

Answer 4

5-15%

Question 5

What is the common age range of affected pigs with PCVAD?

Answer 5

5-12 weeks old

Question 6

Common clinical signs of PCVAD

Answer 6

• Progressive weight loss (wasting)
• Dyspnea
• Visibly enlarged lymph nodes

Question 7

Less frequent clinical signs of PCVAD include:

Answer 7

• Icterus
• Pallor
• Diarrhea

Question 8

Can you assume all herds are affected by PCV2?

Answer 8

Yes - safe to assume this

Question 9

Lesions of PCVAD

Answer 9

• Interstitial pneumonia, necrotizing bronchitis
• Generalized lymphadenopathy
• Basophilic intracytoplasmic inclusion bodies in lymphoid cells
• Lymphocytic hepatitis, nephritis, enteritis

Question 10

Can you use serology for antibody to diagnose PCVAD?

Answer 10

Not really, because this disease is very ubiquitus, and normal pigs may carry antibody.

Question 11

Better ways to diagnose PCVAD than serology:

Answer 11

PCR and immunocytochemistry

Question 12

After vaccines were put on the market, did mortality decrease? Is vaccine use recommended for most herds?

Answer 12

Yes! (decreased from 15-5% to 2-3%) And vaccine use is recommended for most herds - almost 100% of herds are vaccinated!

Question 13

PCVAD frequently coinfects with other ‘intensifier diseases’ - list two examples:

Answer 13

PPV (parvo), PRRSV