Polymers of Life 3: Acylation

Question 1

Definition of acylation

Answer 1

Reaction when you replace a hydrogen with an acyl group

Question 2

General functional group acycl group

Answer 2

= O
II
R-C -

Question 3

Where can acyl groups be found

Answer 3

1. acyl chloride molecule
   = O
   II
   R-C - Cl
2. acid anhydride molecule

= O O
II II
R-C - O - C- R

Question 4

Acyl chloride + alcohol / water = ???

Answer 4

HCl + Ester

Question 5

Acyl chloride + amine = ???

Answer 5

1. HCl + amide
2. Amine act as a base due to lone pair = alkali base + acid ( HCl ) = ammonium salt ( ammonium chloride )

Look at sheet for overall reaction = amide + salt

Question 6

Example of acyl chloride + alcohol

—-> propanoyl chloride + ethanol = ???

Answer 6

=??? Look at sheet

HCl +

Question 7

Example of anyhydride + amine

—-> ethanoic anhydride + methylamine = ???

Answer 7

= ??? Loook at sheet