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HEMATOLOGY 1 > Poikilocytes > Flashcards

Poikilocytes Flashcards

1
Q

Increased number of red cells with variation in shape

A

Poikilocytosis

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2
Q

RBCs almost spherical

A

lacking central pallor

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3
Q

Key area to avoid misidentifying spherocytes in a blood film

A

Feathered edge of the blood film

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4
Q

Condition causing natural RBC death

A

leading to spherocytic red cells

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5
Q

RBCs elongated with a slit-like central pallor

A

also known as mouth cells

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6
Q

Conditions associated with stomatocytes (e.g.

A

Rh deficiency syndrome

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7
Q

Most common form of stomatocytosis

A

characterized by the presence of xerocytes

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8
Q

Dehydrated form of stomatocyte

A

appears half-light and half-dark

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9
Q

RBCs with irregularly spiculated surface

A

also known as thorn cells or spur cells

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10
Q

Condition characterized by defective apo B synthesis and absence of VLDL

A

LDL

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11
Q

Conditions associated with acanthocytes (e.g.

A

McLeod Syndrome

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12
Q

Syndrome with cirrhosis-associated hemolytic anemia and normal platelets

A

TAR syndrome

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13
Q

RBCs with regularly spiculated surface

A

also known as echinocytes

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14
Q

Condition associated with Burr cells

A

characterized by increased plasma urea

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15
Q

Key features of uremia (e.g.

A

normocytic

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16
Q

Enzyme deficiency also associated with Burr cells

A

Pyruvate kinase deficiency

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17
Q

Oval-shaped RBCs associated with hereditary ovalocytosis

A

especially in Southeast Asia

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18
Q

Elliptical (cigar-shaped) RBCs associated with hereditary elliptocytosis and other conditions like thalassemia

A

Elliptocytes

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19
Q

Conditions associated with ovalocytes

A

Hereditary ovalocytosis (Southeast Asian ovalocytosis)

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20
Q

Conditions associated with elliptocytes (e.g.

A

hereditary elliptocytosis

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21
Q

Pear-shaped or teardrop-shaped RBCs

A

also known as tear drop cells

22
Q

Condition associated with dacryocytes

A

characterized by splenomegaly

23
Q

Examples of conditions associated with dacryocytes (e.g.

A

megaloblastic anemia

24
Q

Type of neoplasm PMF is categorized under

A

Myeloproliferative neoplasm (MPN)

25
Q

Peripheral blood smear findings in PMF (e.g.

A

immature granulocytes

26
Q

Fragmented RBCs also known as schizocytes

A

seen in conditions like MAHAs and artificial heart valves

27
Q

Disorders classified as MAHAs characterized by RBC fragmentation and thrombocytopenia (e.g.

A

TTP

28
Q

Condition associated with Escherichia coli O157:H7 infection

A

renal failure

29
Q

Key feature of MAHAs causing RBC fragmentation

A

Narrowing or obstruction of small blood vessels by fibrin or platelet aggregates

30
Q

Specific type of schistocyte with a helmet shape

A

seen in MAHAs

31
Q

Alternative names for DIC

A

characterized by generalized over-activation of coagulation and fibrinolytic systems

32
Q

Tests used to diagnose DIC (e.g.

A

D-dimer test

33
Q

Conditions associated with DIC (e.g.

A

tissue trauma

34
Q

RBCs that are sickle- or crescent-shaped

A

also known as sickle cell menisocytes

35
Q

Conditions associated with drepanocytes (e.g.

A

sickle cell anemia

36
Q

Two forms of drepanocytes

A

irreversible sickle cell and oat-shaped cells.

37
Q

What distinguishes oat-shaped cells from other forms of drepanocytes?

A

Oat-shaped cells have long projections and return to the biconcave disk shape upon reoxygenation.

38
Q

RBCs showing a centrally stained area with a thin outer rim of hemoglobin

A

also known as codocytes or leptocytes

39
Q

Conditions associated with target cells

A

including liver disease and thalassemia

40
Q

Key characteristic of codocytes

A

seen both in vivo and under electron microscopy

41
Q

RBCs with a semicircular defect in their edge

A

resembling a bite mark

42
Q

Condition associated with bite cells

A

Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency

43
Q

RBCs that are folded

A

resembling a biscuit shape

44
Q

Condition associated with biscuit cells

A

Hemoglobin SC disease

45
Q

RBCs with bipolar or central distribution of hemoglobin

A

associated with sickle cell anemia

46
Q

Large pale-pink staining ghost of a red cell

A

seen in malaria and other conditions causing overt hemolysis

47
Q

Alternative names for target cells

A

Codocytes, leptocytes, bull’s eye cells, Mexican hat cells, Greek helmet cells, platycytes

48
Q

Alternative name for stomatocytes

A

Mouth cells

49
Q

Alternative name for helmet cells

A

Helmet-shaped schistocytes

50
Q

Alternative name for dacryocytes

A

Teardrop cells

51
Q

Alternative name for acanthocytes

A

Thorn cells, spur cells

52
Q

Alternative description for schistocytes

A

Fragmented RBCs

HEMATOLOGY 1 (27 decks)

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