plasticity and regeneration

Question 1

What determines gene expression in individual cells

Answer 1

inducing factors: signalling molecules provided by other cells.

competence: ability of a cell to respond to inducing factors which depends on: exact set of surface receptors, transduction molecules and transcription factors expressed by the cell.

Question 2

What is neurogenesis

Answer 2

the process by which neurons are generated.

Question 3

outline neural progenitor cell

Answer 3

only give rise to one class to differentiated progeny

incapable of continuing self-renewal.

Question 4

What are neuroblasts

Answer 4

post mitotic, immature nerve cell that will differentiate into a neuron, fate of migrating neuron will be determined by combination factors e.g. age of precursor cell, position in ventricular zone and enviroment at time of division.

Question 5

mod of brain circuits as a result of experience

Answer 5

constructing brain circuitry rely largely on intrinsic cellular and molecular mechanisms

Question 6

what is the critical period concept

Answer 6

activity mediated influence on the developing brain is most consequential in early life, during temporal windows called critical periods.