Plaelet Studies Flashcards

1
Q

Increase in platelet ass with disease

A

Thrombocytopenia

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2
Q

Increase platelet ct but without disease

A

Thrombocythemia

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3
Q

Nv of platelet

A

200-400,000/mm3

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4
Q

Factors with in increase platelet ct

A

Polycythemia vera
After splenectomy
Thrombocythemia
Among with tb

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5
Q

Factors with decrease in platelet ct

A
Pernicious anemia
Aplastic anemia
Lesion involving MB
Acute leukemia
Idiopathic
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6
Q

Method called in light microscopy

A

Rees and ecjker

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7
Q

Rees and ecker is made up of

A

Brilliant cresyl blue, na citrate, water

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8
Q

2nd light microscopy in method

A

Guy and leake’s method

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9
Q

Diluting fluid of 2nd lightmicroscopy

A

Crystal violet, na citrate and water

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10
Q

Formula of 1st light microscopy

A

Ply counter x 10 x 200 / 4

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11
Q

Formula of 2!nd light microscopy

A

Platelet counter x 10 x 200 x 1

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12
Q

Method under phase microscopy

A
Brencher cronkite
Unopette 
Nygard's
Van allen
Tocantin's
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13
Q

Most accurate method in phase microscopu

A

Brecher cronkite

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14
Q

What diluting fluid used in phase microscopy

A

1% nh4 c204

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15
Q

Nv in phase microscopy

A

150,000-450,000/mm3

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16
Q

Nv in light microscopy

A

140,000-340,000/mm3

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17
Q

Life span of platelet

A

8-11 days

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18
Q

What are the 2 indirect method

A

Damashek

Fonio

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19
Q

Dikuting fluid of damashek’s method

A

Brilliant cresyl blue, na citrate, dw, sucrose, formalin

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20
Q

Nv of damashek

A

500-900,000

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21
Q

Diluting fluid of fonio

A

14% mg2sO4

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22
Q

Counted by means of electronic particle counter

A

Semi automated

23
Q

Counted by means of eptical particle under the principle of dark field microscopy or electronic particle aperture

A

Fully automated

24
Q

Solidifying of blood brought about by different coagulation factors. Esp when the blood is taken out from the body

A

Coagulation

25
Q

Entire mechanism by which bleeding from an injured blood vessel is spontaneously controlled and stop

A

Hemostasis

26
Q

3 general method in coagulation of hemostasis

A

Bleeding time
Clotting time
Clot retraction time

27
Q

Nv of dukes method

A

2-4mins

28
Q

Nv of ivys method

A

1-7mins

29
Q

Puncturing decvuce of ivys method

A

Bard parker blade, sohygmanometer in 40mmhg

30
Q

Uses pre warmed NSS with 37 def temp, dip puncture finger until bleeding stops

A

Copley la litch method

31
Q

Nv of copley la litch

A

3-6mins

32
Q

Patient should abstain taking aspirin in 3 days

A

Aspirin tolerance test

33
Q

If more than 6mins of bt in aspirin tolerance

A

Do not proceed

34
Q

Do the dukes method for bt in what method

A

Aspirin tolerance test

35
Q

Nv of aspirin tolerance test

A

Difference bet 1st and 2nd should not exceed than 2mins

36
Q

It test the ability of the capillary under inc hypoxia and hydrostatic pressure

A

Capillary fragility test

37
Q

Observe of the presence of petechiae

A

Capillary fragility test

38
Q

Get the mid value of of the pt systolic and diastolic pressure, retain those within 5mins and wait for presence of petechia

A

Rumple leede test

39
Q

Nv of petechiometer

A

0-2

40
Q

The pressure is 200nm

A

Suction or petechiometer

41
Q

Time it takes for a fluid blood to solidify after it has been taken out of the body

A

Coagulation time

42
Q

Methods under coagulation time

A
Slide method
Capillary tube method
Lee and white method
Prothrombin time
Partial thromboplastin time
43
Q

Put a drop of blood and fist put every 30 sec, obserbe for fibri trends then stop

A

Slide method

44
Q

Nv of capillary tube method under sabraze

A

3-7mins

45
Q

Nv of slide method

A

2-4mins

46
Q

Uses ordinary capillary tube blue

A

Dale and laidlaw

47
Q

Uses special capillary tube which has wider diameter

A

Sabraze

48
Q

Whole blood clotting time
Prepare 3 test tube 1ml blood each tube
Tilt every 39secs

A

Lee and white method

49
Q

Nv of lee and white method

A

7-15mins

50
Q

Use of measure the extrinsic coagulation system and determine coagulation factor 2,5,7,10

A

Prothrombin time

51
Q

Prothrombine time uses

A

Citrate plasma

52
Q

Nv of prothrombin time

A

10-12 secs

53
Q

Measure intrinsic coagulation system ans will measure deficiency of coag factors 8,9,12,11

A

Partial thromboplastin