Eruthrocyte Studies Flashcards
Include the hemoglobin content, shape, and rate pf rbc
Individual morphology of rbc
Presence of macrocyte and microchte
Debelopmental variation
Under membrane abnormality
Echinocyte Burr cells Acantocyte Elliptocyte Stomatocyte Spur cells
Formation of schistocyte, keratocyte, ghost cell
Trauma
Abnormal hgb content
Drepanocyte, hb cc and hb sc
Type of anemia under elliptocyte
Pernicious anemia
Abnormal wbc ass with PA
Hypersegmented neutrophils with 5-10 lobes
Stomatocyte are what condition
Liver dse or alcoholism
Burst of hgb
Ghost cells
We analyzed the shape, arrangement , color of the cells, number of cells that can be found in the smear
Blood smear distribution
Sickle cells
Drepanocyte or menistocyte
Formation of crystals hexagonal in shape
Hgb C
Finger like projections
Hgb SC
Remnants of nucleus
Howell jolly bodies
Deposition of iron containing bodies
Pappenheimer
Stain under pappenheimer
Perls and prussian blue
Suffering from lead poisoning
Basophilic stippling
Inclusion are categorized in 3
Developmental, abnormal precipitation, presence of parasites
Abnormal precipitation
Heinz bodies
Developmental
Howell jolly, pappenheimer, basophilic stip, and retics
Enlargment of normal size rbc in the presence of
Parasite
Fine reticulum of rna
Reticulocyte
Abnormal precipitation of hgb
Heinz bodies
Parasite invades rbc
Plasmodium
Increase in rbc
Erythrocytosis
Dec of rbc die to reduction of oxygen carrying calacity of the rbc
Anemia
Anemia are decreased in
Rbc ct and hgb
Due to non pathological cause of anemia
Relative anemia
Relative anemia die to what
Pregnancy
High altitude
Menstruation
Defective hgb synthesis
IDA, siderocyte, non geme iron deposit thalassemia
Def in vit b 12 and folic acid
Megaloblastic anemia
Impaired bm fxns
Aplastic anemia Myelopthisic anemia Ineffective hematopoiesis Dec BM stimulation Constitutional anemia Acquired pure red cell aplasia PNH
Young proliferation of cells
Myelopthisic anemia
Dec BM stimulation
Renal failure
Constitutional anemia
Diamond black fan
Acquired pure red cell aplasia
Thymoma
Presence of hemoglobinuria
Paroxysmal nocturnal hemoglobinuria
These are unde hemolytic anemia
Pnh and pch
What are the 2 common ass with dec rbc survival
Instrinsic and extrinsic factor
These are intrinsic factor
Inside rbc problem
Membrane defect
Enzyme defect
Could be due to immune or non immune mechanism
Extrinsic factor
Ab destruction
Immune
Non immune
Hypotonic soln
Blood loss due to
Hemorrhage
If the rpi is lower than 2.0
Ineffective erythropoiesis
Ex of ineffective erythropoiesis
Hypoproliferative anemia
Maturation disorder
If the rpi greater than 3.0
Effective erythropoiesis
Normal MCV, MHCH, MCHC but there is proportionate dec in rbc, hb, hct
Normocytic normochromic
Ex of normocytic normochromic
HA, Sickle cell, hemorrhage
dec of MCV and MCH but normal MCHC
Microcytic normochromic
Ex microcytic normochromic
Chronic inflam
Dec in MCV, MCG, MCHC
Microcytic hypochromic anemia
Ex of microcytic hypochromic
Anemia of chronic dse, thalassemia, IDA, sideroblastic
Inc of MCV and MCH but normal MCHC
MAcrocytuc normochromic
Ex pf macrocytic normochromic
PA
Inc of MCV but dec of MCH and MCHC
Macrocytic hypochromic
Ex of macrocytic hypochromic
Folate def
The description of individual dell size and is yhe best index for classifying anemias. Express the volume occupied by a single red cell
Mean corpuscular volume
Ref range of MCV
82-92fl
Measure of the average wt of hgb in the rbc is of value in diagnosing severely anemic pt
Mean corpuscular hgb
Ref range of mc hgb
27-32
Due to dec of rbc production
Aplastic anemia
Due to hemolysis of rbc
Aplastic anemia and spherocytes
Due to nuclear maturation abnormality
Pernicious anemia
Due to cytoplasmic maturation
Thalassemia and IDA