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Hema 2 > Disorder Of Primary And Platelet > Flashcards

Disorder Of Primary And Platelet Flashcards

1
Q

Hemorrhage of blood ino areas of skin, mucous membranes and other tissue

A

Purpura

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2
Q

Form of purpura in which blood escape inti large areas of skin and mucous membrane but into deep tissues

A

Ecchymosis

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3
Q

Nosebleed

A

Epistaxis

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4
Q

Leakage of blood into join cavities

A

Hemarthrosis

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5
Q

Vomits of blood

A

Hematemesis

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6
Q

Swelling or tumor in the tissues or a body cavities that contains clotted blood

A

Hematoma

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7
Q

Hemoglobin in the urine

A

Hemoglobinuria

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8
Q

Stool containing dark or black blood

A

Melena

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9
Q

Excessive menstrual bleeding

A

Menorrhagia

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10
Q

Present of urea in urine

A

Uremia

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11
Q

Disorder of primary hemostasis

A

Vascular disorder

Platelet disorder

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12
Q

Purplish red pinpoint hemorrhagic spots in the skin caused by loss of capillary ability to withstand nomal blood pressure and trauma

A

Petechiae

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13
Q

Other name for hereditary hemorrhagic telangiectasia

A

Osler weber rendu disease

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14
Q

Other name for congenital hemangiomata

A

Kasaback merritt syndrome

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15
Q

Condition of increase bascular fragility

A

Ehlers Danlos syndrome

Marfan’s syndrome

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16
Q

Tumor composed of blood vessel

A

Congenital hemangiomata

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17
Q

Most common inherited vascular disorder the blood vessel walls are thin and lacks smooth muscle

A

Hereditary hemorrhagic telangiectasia

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18
Q

Elastic fiber in small arteries are calcified and structurely abnormal

A

Pseudoxanthoma elasticum

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19
Q

Degradation of collagen and elastin

A

Senile purpura

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20
Q

Deficiency of vitamin C/ascorbic acid

A

Scurvy

21
Q

Immunilogic damage to endothelial cell

A

Henoch schonlein purpura

22
Q

What ere the 3 hereditary qualitative platelet disorder

A

Platelet adhesion
Platelet aggregation
Platlet secretion/storage pool defect

23
Q

What are the diorder under platelet aggregation

A

Glanzmann’s thrombasthenia

24
Q

Qualitative disirder of platelet secretion/storage pool defect

A

Gray platelet
Hermansky pudlak
Wiskott aldrich
Chediak higaski

25
Q

Qualitative hereditary disorder for platelet adhesion

A

vWD

Bernard soulier

26
Q

Abnormal in vWD

A

Ristocetin

27
Q

Lack of vwf fro normak platelet adhesion

A

vWD

28
Q

Platelet aggregation test for vwd

A

Normal platelet aggregation test with epinephrine collagen ADP

29
Q

Def gp1b (receptor for vwf) giant platelet syndrome

A

Bernard soulier

30
Q

Platelet aggregation test for bernard soulier

A

Normal platelet aggregation with ECA

31
Q

Abnormal in bernard soulier

A

Ristocetin

32
Q

What are the acquired qualitative disorder

A 
Uremia
Paraproteinemias
Acute myeloblastic leukemia
Myeloproliferative disorder
Drugs
33
Q

Abrnormal protein condition characterized by coating of platelet membrane with abnormal protein

A

Paraproteinemias

34
Q

Condition is characterized by the presence of abnormal megakaryocyte

A

Acute myeloid leukemia

35
Q

Needed for normal plateleet aggregation

A

Fribrinogen

36
Q

Def in gpllb-llla conplex

A

Glanzmann’s thrombasthenia

37
Q

Ph receptor fro fibrinogen

A

Gpllb-llla complex

38
Q

Platelet aggregation test for glanzmann’s thrombasthenia

A

Normal platelet aggregatio with ristocetin

39
Q

Abnormal of glanzmann’s thrombasthenia

A

ECA

40
Q

Decrease b, production

A

Thrombocytopenia

41
Q

Quantitative disorsers

A

Thrombocytosis

Thrombocytopenia

42
Q

Example of dilusion loss of plt ct

A

Mass blood transfusion

43
Q

Example of increase pltls squestion of spleen

A

Splenomegaly

44
Q

Example of due to dec of bm activity

A

Aplastic anemia

Pancytopenia

45
Q

Example of dec survival time

A

DIC

inc ITP destruction

46
Q

Auto ab for platelets

A

Immune thrombocytopenic purpura

47
Q

Mass consumption of platelets

A

Disseminated intravascular coagulation

48
Q

Dec in all froms of blood cells plt wbc, rbc

A

Pacytopenia

Hema 2 (10 decks)

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