Pituitary and Thyroid

Question 1

ACTH

Answer 1

stimulated by Corticotropin-releasing hormone (CRH) and binds to receptor in adrenal cortex

release adrenocorticosteroids and adrenal androgens (cortisol)

used to dx addisons (primary) vs secondary adrenal insufficiency

Question 2

GH/Somatotropin

Answer 2

decreases with age and promotes cell proliferation, bone growth, and cartilage synthesis

Question 3

Gonadodropins

Answer 3

LH + FSH

GnRH: release FSH/LH via pulse dose because a continuous dose will inhibit release

Question 4

Prolactin

Answer 4

inhibited by DA and stimulates lactation and reproductive/immune system

Question 5

TSH

Answer 5

uptake of iodide to get T3/T4

Question 6

HT Hormones

Answer 6

GH releasing/inhibiting hormone

Gonadotropin R/I hormone

Corticotropin R/I hormone

Thyrotropin R/I hormone

Question 7

Oxytocin

Answer 7

stimulate uterine contraction and milk ejection and induce full term labor

Question 8

Vasopressin/ADH

Answer 8

increase water permeability and reabsorption in kidney (retain water) and cause constriction of vascular smooth muscle (increase BP)

Question 9

Levothyroxine

Answer 9

T4 supplement

Question 10

Liothyronine

Answer 10

T3 supplement

Question 11

Radioactive Iodine

Answer 11

treat hyperthyroidism by destroying TG

Question 12

Methimazole and Propylthiouracil

Answer 12

inhibit TH synthesis

Question 13

Iodide

Answer 13

block hormone release and inhibit production of TH