Arrhythmia + Angina Flashcards
Disopyramide
Class 1a Sodium Channel Blocker
Binds to sodium + potassium channels and inhibits K+ efflux to slow conduction of phase 0 and slow repolarization of phase 3 which increases AP/RP duration
Quinidine
Class 1a Sodium Channel Blocker
Binds to sodium + potassium channels and inhibits K+ efflux to slow conduction of phase 0 and slow repolarization of phase 3 which increases AP/RP duration
Procainamide
Class 1a Sodium Channel Blocker
Binds to sodium + potassium channels and inhibits K+ efflux to slow conduction of phase 0 and slow repolarization of phase 3 which increases AP/RP duration
Lidocaine
Class 1b Sodium Channel Blocker
Bind only to sodium channel but increases K+ efflux
which slows conduction of phase 0 and decreases AP/RP duration
Mexiletine
Class 1b Sodium Channel Blocker
Bind only to sodium channel but increases K+ efflux
which slows conduction of phase 0 and decreases AP/RP duration
Tocainide
Class 1b Sodium Channel Blocker
Bind only to sodium channel but increases K+ efflux
which slows conduction of phase 0 and decreases AP/RP duration
Flecainide
Class 1c Sodium Channel Blocker
Binds to both sodium and potassium channels but no effect on potassium channels
Propafenone
Class 1c Sodium Channel Blocker
Binds to both sodium and potassium channels but no effect on potassium channels
Class 2: Beta Blockers
depress automaticity of SA node, prolong conduction of AV node, and decrease contractility + HR
Amiodarone
Class 3: Potassium Channel Blockers that inhibit K+ efflux which prolong AP/RP duration
Dronedarone
Class 3: Potassium Channel Blockers that inhibit K+ efflux which prolong AP/RP duration
Sotalol
Class 3: Potassium Channel Blockers that inhibit K+ efflux which prolong AP/RP duration
Ibutilide
Class 3: Potassium Channel Blockers that inhibit K+ efflux which prolong AP/RP duration
Dofetilide
Class 3: Potassium Channel Blockers that inhibit K+ efflux which prolong AP/RP duration
Diltiazem + Verapamil
Class 4: Calcium Channel Blockers
Arrhythmia Treatment
