Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Systemic Pharm II > Blood Drugs + Hyperlipidemia > Flashcards

Blood Drugs + Hyperlipidemia Flashcards

1
Q

Aspirin

A

Platelet Inhibitors

Inhibit Cox-1 to inhibit thromboxane A2 which inhibits clot formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ticlopidine

A

Platelet Inhibitor

ADP Receptor Blocker which prevents expression of fibrinogen GPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Prasugrel

A

Platelet Inhibitor

ADP Receptor Blocker which prevents expression of fibrinogen GPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Clopidogrel

A

Platelet Inhibitor

ADP Receptor Blocker which prevents expression of fibrinogen GPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ticagrelor

A

Platelet Inhibitor

ADP Receptor Blocker which prevents expression of fibrinogen GPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Abciximab

A

Platelet Inhibitor

GPR Blocker - directly inhibits fibrinogen from binding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tirofiban

A

Platelet Inhibitor

GPR Blocker - directly inhibits fibrinogen from binding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Eptifibatide

A

Platelet Inhibitor

GPR Blocker - directly inhibits fibrinogen from binding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Argatroban

A

Anticoagulant

Direct Thrombin Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Bivalirudin

A

Anticoagulant

Direct Thrombin Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Lepirudin

A

Anticoagulant

Direct Thrombin Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Desirudin

A

Anticoagulant

Direct Thrombin Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Dabigatran

A

Anticoagulant

Direct Thrombin Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Apixaban

A

Anticoagulant

Factor Xa Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fondaparinux

A

Anticoagulant

Factor Xa Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rivaroxaban

A

Anticoagulant

Factor Xa Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

-PARIN Drugs

A

LMWH

Bind to antithrombin III and inactivate Factor Xa

18
Q

Heparin

A

Binds to antithrombin III and increases its activity which inactivates thrombin and Factor Xa

19
Q

Warfarin

A

Inhibits vitamin K epoxide reductase which decreases vitamin K which will decrease coagulation factors

20
Q

Urokinase

A

Thrombolytic Agent

Produced by kidney and cleaves the A-V bond in plasminogen to form plasmin

21
Q

Streptokinase

A

Thrombolytic Agent

Forms active complex with plasminogen and catalyzes degradation of fibrinogen etc

22
Q

Alteplase

A

Thrombolytic Agent

Activates plasminogen bound to fibrin in a thrombus

23
Q

Retaplase

A

Thrombolytic Agent

24
Q

Tenecteplase

A

Thrombolytic Agent

Binds to fibrin and converts plasminogen to plasmin

25
Q

Aminocaproic Acid

A

inhibit plasminogen from activating

Treats bleeding

26
Q

Protamine

A

heparin antagonist

27
Q

Vitamin K

A

antagonizes warfarin

28
Q

-STATIN drugs

A

HMG CoA Reductase Inhibitor
Decrease LDL levels by A LOT
contraindicated in teens, children, pregnancy, lactation

29
Q

Niacin

A

inhibits VLDL excretion which lowers LDL but mainly increases HDL

30
Q

What are the AE of Niacin?

A

flushing, warmth, abdominal pain, nausea, and hyperuricemia

31
Q

Colestipol

A

Bile Acid Sequesters

Bind to bile salts so that liver must convert cholesterol to bile (decreases LDL)

32
Q

Colesevelam

A

Bile Acid Sequesters

Bind to bile salts so that liver must convert cholesterol to bile (decreases LDL)

33
Q

Cholestyramine

A

Bile Acid Sequesters

Bind to bile salts so that liver must convert cholesterol to bile (decreases LDL)

34
Q

Gemfibrozil

A

Fibrates
Increase expression of lipoprotein lipase and increase oxidation of FA (TG) in livers
(Decrease TG)

35
Q

Fenofibrate

A

Fibrates
Increase expression of lipoprotein lipase and increase oxidation of FA (TG) in livers
(Decrease TG)

36
Q

Ezetimibe

A

Cholesterol Absorption Inhibitor

mild effects

37
Q

What are the contraindications for HMG Coa Reductase Inhibitors

A

pregnancy, lactation, child-teens

38
Q

What are the effects of statin

A

DECREASE LDL levels

plaque stabilization, increase blood sugar levels, increase warfarin levels, improve coronary endothelial function and inhibit platelet thrombus

39
Q

What are the adverse effects and contraindications for Fibrates

A

Contraindicated in patients with kidney or liver dysfunction or history of gallbladder disease

AE: GI disturbances, gallstones, inflammation of voluntary muscle and compete with warfarin

40
Q

What are the contraindications for ezetimibe

A

contraindicated in patients with liver (hepatic) dysfunction

41
Q

What are the side effects of Niacin

A

flush and warmth, nausea and abdominal pain and hyperuricemia

Systemic Pharm II (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions