Physiology: Skeletal Muscle 2 Flashcards

1
Q

what effect will more motor units have on the strength of contraction

A

greater strength

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2
Q

how is a stronger contraction achieved

A

stimulation of more motor unitrs (recruitment)

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3
Q

what is the purpose of asynchonrous motor unit recruitment

A

occurs during submaximal contractions to help prevent muscle fatigue

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4
Q

what 4 things does muscle tension depend on

A
  • frequency of stimulation
  • summation of contractions
  • length of muscle fibre at onset of contraction
  • thickness of muscle fibre
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5
Q

define twitch summation

A

muscle fibre restimulated before it has completely relaxed, the second twitch is adding on to the first one resulting in summation

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6
Q

what is a tetanic contraction

A

muscle fibre is stimulated so rapidly that it doesnt have the chance to relax between the stimuli, and a maximal sustained contraction occurs - known as tetanus

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7
Q

why can cardiac muscle not be tetanised

A

due to refractory period

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8
Q

describe the relation between tension developed in skeletal muscle and frequency of stimulation

A

as frequency of stimulation inc tension developed by skeletal muscle inc

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9
Q

what is skeletal muscles optimum length for maximal tetanic contraction

A

resting condition - optimal overlap between actin and myosin

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10
Q

define isotonic contraction

A

muscle tension remains constant and muscle length changes

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11
Q

define isometric contraction

A

muscle tension develops at constant muscle length

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12
Q

how is tension transmitted to bone

A

via elastic components of muscle

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13
Q

give an example of when isometric contraction used

A

maintaining body posture

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14
Q

give an example of when isotonic contraction used

A

moving object (flexing)

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15
Q

describe the relation ship between velocity of muscle shortening and load

A

the velocity of shortening decreases as the load increases

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16
Q

at maximum load what happens to shortening

A

0 velocity of shortening (cant move) - isometric contraction

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17
Q

muscles that can do what are more resistant to fatigue

A

have a greater capacity to synthesise ATP

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18
Q

what determines the speed of contraction

A

activity of myosin ATPase - determines speed at which energy is made available for cross bridge recycling

19
Q

what are the 3 metabolic pathways that supply ATP in the muscle fibre

A

transfer of high energy phosphate from creatinine phosphate to ADP oxidative phosphorylation (O2 present) glycolysis (O2 not present)

20
Q

name the types of fibres

A

I - slow oxidative

IIa - fast oxidative

IIx - fast glycolytic (white)

21
Q

what are the I fibres used for

A

prolonged low work aerobic activities eg walking

22
Q

what are the IIa fibres used for

A

aerobic and anaerobic metabolism - prolonged moderate work eg jogging

23
Q

what are IIx fibres used for

A

anaerobic metabolism - short term high intensity activities eg jumping

24
Q

what type of reflex is the stretch reflex

A
  • monosynaptic
  • negative feedback that resists passive change in muscle length to maintain optimal resting length of muscle
25
Q

what is the sensory receptor for the stretch reflex

A

muscle spindle - activated my muscle stretch

26
Q

describe the stretch reflex

A
  • negative feedback that resists passive change in muscle length to maintain optimal resting length of muscle, helps to maintain posture when walking eg
  • muscle spindle activated by muscle stretch increases firing in afferent neurones
  • synapse with the spinal cord with alpha motor neurones (efferent)
  • contraction of stretched muscle
27
Q

how can the stretch reflex be ellicited

A

tapping muscle eg patellar tendon, this rapidly stretches the muscle

28
Q

what are muscle spindles known as

A

intrafusal fibres

29
Q

what are ordinary muscle fibres referred to as

A

extrafusal fibres

30
Q

how do muscle spindles run in relation to ordinary muscle fibres

A

parallel within belly of muscles

31
Q

what are muscle spindles sensory nerve endings known as

A

annulospiral fibres

32
Q

what are muscle spindles

A

sensory receptors for stretch reflex

33
Q

what happens to the muscle spindles when the muscle is stretched

A

the discharge from the sensory endings (annulospiral fibres) is increased

34
Q

what are the efferent neurones that supply muscle spindles

A

gamma motor neurones - own efferent motor nerve neurones

35
Q

what do the gamma motor neurones do

A

adjust the level of muscle tension in the spindles to maintain their sensitivity when the muscle shortens during contraction

36
Q

does the contraction of intrafusal fibres contribute to overall strength of muscle contraction

A

no

37
Q

what does a electromyography do

A

detect the presence of muscular activity - record frequency and amplitude of muscle fibres action potentials

38
Q

what is the use of EMG

A

differentiate primary muscle disease from muscle weakness caused by neurological disease

39
Q

knee jerk spinal segments

A
40
Q

ankle jerk

A

S1 and 2, tibial nerve

41
Q

biceps jerk

A

C5-6, musculocutaenous nerve

42
Q

brachioradialis

A

C5-6, radial nerve

43
Q

triceps jerk

A

C6-7 - radial nerve