Physiology: Skeletal Muscle 2 Flashcards
what effect will more motor units have on the strength of contraction
greater strength
how is a stronger contraction achieved
stimulation of more motor unitrs (recruitment)
what is the purpose of asynchonrous motor unit recruitment
occurs during submaximal contractions to help prevent muscle fatigue
what 4 things does muscle tension depend on
- frequency of stimulation
- summation of contractions
- length of muscle fibre at onset of contraction
- thickness of muscle fibre
define twitch summation
muscle fibre restimulated before it has completely relaxed, the second twitch is adding on to the first one resulting in summation

what is a tetanic contraction
muscle fibre is stimulated so rapidly that it doesnt have the chance to relax between the stimuli, and a maximal sustained contraction occurs - known as tetanus

why can cardiac muscle not be tetanised
due to refractory period
describe the relation between tension developed in skeletal muscle and frequency of stimulation
as frequency of stimulation inc tension developed by skeletal muscle inc
what is skeletal muscles optimum length for maximal tetanic contraction
resting condition - optimal overlap between actin and myosin
define isotonic contraction
muscle tension remains constant and muscle length changes
define isometric contraction
muscle tension develops at constant muscle length
how is tension transmitted to bone
via elastic components of muscle
give an example of when isometric contraction used
maintaining body posture
give an example of when isotonic contraction used
moving object (flexing)
describe the relation ship between velocity of muscle shortening and load
the velocity of shortening decreases as the load increases

at maximum load what happens to shortening
0 velocity of shortening (cant move) - isometric contraction
muscles that can do what are more resistant to fatigue
have a greater capacity to synthesise ATP
what determines the speed of contraction
activity of myosin ATPase - determines speed at which energy is made available for cross bridge recycling
what are the 3 metabolic pathways that supply ATP in the muscle fibre
transfer of high energy phosphate from creatinine phosphate to ADP oxidative phosphorylation (O2 present) glycolysis (O2 not present)
name the types of fibres
I - slow oxidative
IIa - fast oxidative
IIx - fast glycolytic (white)
what are the I fibres used for
prolonged low work aerobic activities eg walking
what are the IIa fibres used for
aerobic and anaerobic metabolism - prolonged moderate work eg jogging
what are IIx fibres used for
anaerobic metabolism - short term high intensity activities eg jumping
what type of reflex is the stretch reflex
- monosynaptic
- negative feedback that resists passive change in muscle length to maintain optimal resting length of muscle
what is the sensory receptor for the stretch reflex
muscle spindle - activated my muscle stretch
describe the stretch reflex
- negative feedback that resists passive change in muscle length to maintain optimal resting length of muscle, helps to maintain posture when walking eg
- muscle spindle activated by muscle stretch increases firing in afferent neurones
- synapse with the spinal cord with alpha motor neurones (efferent)
- contraction of stretched muscle
how can the stretch reflex be ellicited
tapping muscle eg patellar tendon, this rapidly stretches the muscle
what are muscle spindles known as
intrafusal fibres
what are ordinary muscle fibres referred to as
extrafusal fibres
how do muscle spindles run in relation to ordinary muscle fibres
parallel within belly of muscles
what are muscle spindles sensory nerve endings known as
annulospiral fibres
what are muscle spindles
sensory receptors for stretch reflex
what happens to the muscle spindles when the muscle is stretched
the discharge from the sensory endings (annulospiral fibres) is increased
what are the efferent neurones that supply muscle spindles
gamma motor neurones - own efferent motor nerve neurones
what do the gamma motor neurones do
adjust the level of muscle tension in the spindles to maintain their sensitivity when the muscle shortens during contraction
does the contraction of intrafusal fibres contribute to overall strength of muscle contraction
no
what does a electromyography do
detect the presence of muscular activity - record frequency and amplitude of muscle fibres action potentials
what is the use of EMG
differentiate primary muscle disease from muscle weakness caused by neurological disease
knee jerk spinal segments

ankle jerk
S1 and 2, tibial nerve
biceps jerk
C5-6, musculocutaenous nerve
brachioradialis
C5-6, radial nerve
triceps jerk
C6-7 - radial nerve