Physiology-Renal Checkpoint Quiz Flashcards
Which of the following layers of the glomerular capillary membrane restrict solute movement by both size and charge selectivity?
- endothelium
- basement membrane
- epithelial
- podocyte
Basement membrane
Specialized cells of the thick ascending loop of henle or distal tubule adherent to every glomerulus at site between afferent and efferent arterioles that regulate glomerular filtration are called
Macula densa cells
Which of the following serves as primary means for physiologic regulation of glomerular filtration rate?
- glomerular capillary filtration coefficient
- glomerular hydrostatic pressure
- hydrostatic pressure in bowman’s capsule
- colloid osmotic pressure of glomerular capillary plasma proteins
- colloid osmotic pressure of proteins in bowman’s capsule
Glomerular hydrostatic pressure
Constriction of afferent arteriole would result in what change to GFR
- increase in GFR
- decrease n GFR
- depends on degree of dilation
- no change
Decrease in GFR
A reduction in the delivery of NaCl to macula densa would result in which of he following?
- efferent arteriole dilation with decrease in GFR to normal
- efferent arteriole constriction with an increase in GFR to normal
- afferent arteriole dilation with an increase in GFR to normal
- afferent arteriole constriction with decrease in GFR to normal
Afferent arteriole dilation with increase in GFR to normal
Angiotensin II causes which of the following in order to normalize GFR in states of decreased RBF?
- efferent arteriole dilation with decrease in GFR to normal
- efferent arteriole constriction with increase in GFR to normal
- afferent arteriole dilation with increase in GFR to normal
- afferent arteriole constriction with decrease in GFR to normal
Efferent arteriole constriction with increase in GFR to normal
Which of the following is not reabsorbed in the proximal tubule?
- Na
- HCO3
- glucose
- H
H
“Highly permeable to water, but impermeable to NaCl” describes which of the following tubular segments?
- proximal tubule
- descending limb of loop of henle
- ascending limb of loop of henle
- distal tubule
Descending limb of loop of henle
The site of action of aldosterone is on which of the following tubular segments?
- proximal tubule
- descending limb of loop of henle
- ascending limb of loop of henle
- collecting duct
Collecting duct
Name the 3 major factors of autoregulation
Myogenic reflex of afferent arteriole
Tubuloglomerular feedback
Angiotensin II mediated vasoconstriction of efferent arteriole
Increased NaCl delivery to macula densa promotes ______
Vasoconstriction of afferent arteriole
A decrease in blood pressure would evoke a _______ of the afferent arteriole
Reflex vasodilation
During states of reduced renal blood flow, what substance is released from granular cells within wall of afferent arteriole?
Renin
How does angiotensin II normalize GFR in states of decreased RBF?
Causes vasoconstriction of efferent arteriole (increasing glomerular capillary hydrostatic pressure and hence, GFR)
When there is a water deficit in the body, osmolarity will be high, kidney should respond by secreting what kind of urine?
Concentrated
