Physiology Length-Tension Relationship Flashcards

0
Q

Total tension=

A

Active tension + passive tension

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1
Q

Length tension relationship

A

Relationship between the resting length of the muscle at rest before a contraction, and the force developed upon contraction from that resting length

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2
Q

Active tension is due to

A

Crossbridge cycling

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3
Q

Passive tension is due to

A

Series elastic element (SEE)

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4
Q

What is happening with crossbridge activity when actin and myosin have less overlap?

A

There is less crossbridge activity

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5
Q

More crossbridges= (more/less) force?

A

More

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6
Q

What trauma is likely to occur when actin and myosin fibers do not have much overlap when muscle contraction begins?

A

Tearing

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7
Q

Stretch insufficiency

A

Less force development due to muscle being in a stretched position at beginning of contraction

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8
Q

Crossbridge polarity

A

Crossbridges are only able to push in one direction: toward center of sarcomere

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9
Q

Muscle shorten weakness

A

Muscle weakness due to contraction beginning when the sarcomere is shorter than normal

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10
Q

Underlying causes of muscle shorten weakness

A

1 Crossbridges are pushing against each other because actin can’t really go anywhere
2 Myosin filaments are impinging which will also mechanically interfere with force development

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11
Q

Load

A

Amount of force developed by the muscle

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12
Q

Velocity

A

Velocity of muscle shortening

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13
Q

What is it called when the velocity of shortening is 0?

A

Isometric

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14
Q

What happens as load decreases?

A

Velocity of muscle shortening increases

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15
Q

Why does smooth muscle have its name?

A

No striations, like skeletal muscle has

16
Q

Does smooth muscle have actin and myosin filaments?

A

Yes, just not in the arrangement seen in skeletal muscle

17
Q

Does smooth muscle have sarcoplasmic reticulum? Why?

A

No.

  1. Cells are much smaller than muscle cells, so they are able to depend only on the calcium diffusing from outside
  2. Smooth muscle is not required to have rapid contraction
18
Q

Does smooth muscle have troponin and tropomyosin?

A

No

19
Q

Calmodulin

A

Protein in smooth muscle cells that regulates the contraction

20
Q

Process of muscle contraction in smooth muscle

A
  1. Calcium attaches to calmodulin
  2. Calmodulin attaches to inactive myosin light chain kinase (MLCK) on S2 head, activating it
  3. MLCK cleaves ATP
  4. Crossbridge cycling occurs
21
Q

Study graphs

A

Load velocity relationship
Length tension curve
Length tension relationship

22
Q

Where does most alcohol absorption occur?

A

Small intestine