Physiology Of Olfaction And Gustation Flashcards
What are Ordorants?
They are airborne molecules and they give off vapor they reach the olfactory breceptors by being inhaled through the nose and through mouth the vapors circulate the throat
What is Olfaction?
It is the sense of smell and involves olfactory receptors responding to chemical stimuli
Made possible by the olfactory bulbs and olfactory membrane
What two layers make up the olfactory membrane?
Olfactory epithelium and Lamina propria
What is the olfactory epithelium?
Yellowish pigmented epithelium in the roof of the nasal cavity near the septum smell is detected by the olfactory chemoreceptors which are specialized endings of bipolar neurons that convert olfactory stimuli into nerve impulses
What does the olfactory epithelium contain?
Olfactory sensory neurons
Supporting cells
Basal stem cells
What does the olfactory epithelium cover?
Cribriform plate
Superior portion of the perpendicular plate
Superior nasal conchae of ethmoid bone
What does the lamina propria contain?
Areolar tissue
Blood vessels
Nerves
Olfactory glands
What are the purpose of the secretions of the olfactory glands?
They absorb water and form an think pigmented mucus that coats surface if the olfactory organs
What is the description of the olfactory sensory neurons?
The Cillian is unmyelenated and they contain olfactory receptors
A single axon passes through cribriform plate of the ethmoid bone and enter the olfactory bulbs
What is olfactory discrimination?
Can distinguish thousands of chemical stimuli and cns interprets smells by pattern of receptor activity
Where does olfactory reception occur?
On the surface membranes of the olfactory cilia
How does odorant discrimination occur?
Oforants interact with odorant binding proteins on the membrane surface and adenylyl cyclase activates and this is an enzyme that converts ATP to cAMP
CAMP will open sodium channels in the Plasma membrane which will depolarize
Sufficient depolarization occurs an action potential is triggered in the axon and information is relayed to CNS
How many odorant can activate olfactory receptors?
4 odorants
What do the axons leaving the olfactory epithelium do?
Collect into 20 or more bundles
Penetrate the cribriform plate of ethmoid bone and will reach the olfactory bulbs of the cerebrum where it will synapse in the Golmeruli
How does transmission of olfactory signal to olfactory bulb occur?
The axons of the receptors cells penetrate the cribriform plate and form the olfactory nerve
They synapse on Mitral cells in the olfactory bulb which is superior to cribriform plate
The axons of Mitral cells travel the olfactory tract to reach olfactory cortex and the limbic system