Physiology of lipid disorders

Question 1

Which volatile fatty acids are glucogenic (used to generate glucose) and which are ketogenic (used to generate ketones)

Answer 1

Glucogenic = proprionate
Ketogenic = acetate + butyrate

Question 2

what is the effect of too many free fatty acids for the liver to process?

Answer 2

Excess FAs converted back into TG and stored in hepatocytes => hepatic lipidosis

Question 3

What is the effect of too much acetyl CoA for available oxaloacetate?

Answer 3

Excess acetyl CoA is diverted into ketones