physiology of blood pressure Flashcards
formula for mean systemic arterial (MAP)
MAP=COxTPR
what does autonomic control influence (BP related)
cardiac output and vascular resistance
what does long term response in kidney influence BP related
vascular resistance
what is the fundamental role of the kidney
- filtration
- reabsorption
- excretion
what is glomerular filtration rate
a test that estimates how much blood passes through the glomeruli each minute (how well the kidneys work)
what are the three basic renal processes
- glomerular filtration
- tubular reabsorption
- tubular secretion
is GFR usually high or low
very high, around 180L/day
means there’s lots of opportunity to regulate EFC composition and get rid of unwanted substances
is it the EFC that is regulated or the urine
the EFC
do kidneys have good or bad blood supply
really good
0.5% total body weight but 20% of CO
what does GFR regulate
hormonal release
what does the macula densa do
senses GFR by Na+
what does the juxtaglomerular (JG) apparatus include
JG cells that secrete renin
what are the most important hormones involved in the control of BP
- ADH (vasopressin)
- angiotensin II
- aldosterone
- atrial natriuretic peptide (ANP)
what is the principal facto controlling Ang II levels
renin release
how does decreased circulating Ang II volume stimulate renin release
through
- decreased BP
- decreased NaCl at macula densa
- decreased renal perfusion pressure