neuronal control of the CV and rest systems Flashcards
step 1 of neuronal function
neurotransmitters act on receptors in dendritic spines
step 2 of neuronal function
depolarisation
step 3 of neuronal function
action potential generation and propagation
step 4 of neuronal function
neurotransmitter release signals to:
- neurons
- glands
- muscles
CNS neurotransmittes
- glutamate
- GABA
- serotonin
- dopamine
- noradrenaline
PNS neurotransmitters
- noradrenaline
- acetylcholine
what does the ANS do
regulates certain body processes that work without conscious effort
eg. blood pressure
rate of breathing
what are acetylcholine and norepinephrine/noradrenaline used for
effecting autonomic activity, they bind to specific receptors to cause a response
which receptors do ACh bind to
muscarinic receptors
what receptors do norepinephrine and noradrenaline bind
adrenergic receptors
what primarily innervates vascular smooth muscle
the sympathetic nervous system through adrenergic receptors
what are the three types of adrenoceptors present in vascular smooth muscle cells
alpha 1 (a1)
alpha 2 (a2)
beta 2 (b2)
what is the main endogenous agonist of a1, a2 and b2
noradrenaline(NA)/norepinephrine(NE)
effect of binding at b1 receptor in the sinoatrial node & ventricles (sympathetic)
it increases heart rate and increases force of contraction in heart\
parasympathetic has opposite effect
effect of binding at a1 receptor in the arteries going to intestine and kidneys (sympathetic)
the vessels going to the intestine and kidneys are constricted
parasympathetic has opposite effect