cardiovascular sensory regulation & control Flashcards

1
Q

how is blood pressure and blood flow controlled

A

through interconnected neg feedback systems that work by adjusting HR, SV, systemic vascular resistance and blood volume

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2
Q

do all feedback systems act at the same speed

A

no some act faster or slower

some are also shorter or longer than others

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3
Q

where is the cardiovascular centre found

A

in the medulla oblongata

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4
Q

what does the cardiovascular centre do

A

regulate HR and SV

controls neural, hormonal and local neg feedback systems that regulate blood pressure and blood flow to specific tissues

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5
Q

what do groups of neurones in the CV centre do

A

regulate HR, contractility of ventricles and blood vessel diameter

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6
Q

where are cardio-stimulatory and cardio-inhibitory centres found

A

in the CV centre

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7
Q

what does vasomotor centre do

A

control blood vessel diameter

receives input from both higher brain region and sensory receptors

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8
Q

3 main types of sensory receptors

A

proprioceptors

baroreceptors

chemoreceptors

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9
Q

what do proprioceptors do

A

monitor movements of joints and muscles to provide input during physical activity

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10
Q

what do baroreceptors do

A

monitor pressure changes and stretch in blood vessel walls

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11
Q

what do chemoreceptors do

A

monitor concentration of various chemicals in the blood

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12
Q

what does the output from CV travel along

A

neurons of ANS

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13
Q

what does the sympathetic (stimulatory) system oppose

A

the parasympathetic system (inhibitory)

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14
Q

where are baroreceptors found

A

found internal carotid arteries and other large arteries in neck and chest

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15
Q

what does the carotid sinus reflex do

A

helps regulate blood pressure in brain

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16
Q

what does the aortic reflex do

A

regulate systemic blood pressure

17
Q

what happens in baroreceptor reflexes when BP falls

A

baroreceptors stretched less which leads to slower rate of impulses to CV centre

18
Q

what does CV centre do once receiving signals from baroreceptor

A

decrease parasympathetic stimulation and increases sympathetic stimulation

19
Q

where are chemoreceptors found

A

close to baroreceptors of carotid sinus and aortic arch

20
Q

what do chemoreceptors do

A

detect
- hypoxia (low O2)
- hypercapnia (high CO2)
- acidosis (high H+)

and send signals to CV

21
Q

what does cv centre do after receiving signals from chemoreceptors

A

it increases sympathetic stimulation to arterioles and veins

produces vasoconstriction and an increase in BP

22
Q

what does martial natriutertic peptide (ANP) promote

A

natriuresis (loss of sodium)

23
Q

what does the atrial myocytes do

A

synthesise, store and release ANP in response to stretch

24
Q

what is the effect of natriuresis

A

renal vasodilation

increased blood flow= increased GFR

means more Na+ reaches macula densa meaning more Na+ secreted

25
Q

what can ANP inhibit

A

actions of renin and generally opposes effects of angiotensin II

26
Q

how does systemic control of arteriolar diameter occur

A

by sympathetic innervation

27
Q

what does tonic release or norepinephrine do
(systemic control of AD)

A

binds of a-adrenergic receptors on vascular smooth muscle

helps maintain tone of arterioles

28
Q

what happens when sympathetic release of norepinephrine decreases

A

the arterioles dilate and vice versa

29
Q

how does local control of AD work

A

by paracrine factors
- vascular endothelium
- low O2 and high CO2
- active hyperaemia
- reactive hyperaemia

30
Q

what is the vascular endothelium sensitive to

A

pressure and flow

31
Q

what is the vascular endothelium the major determinant of

A

vascular resistance

32
Q

stages of active hyperaemia

A
  1. increase of tissue metabolism
  2. increase in release of metabolic
    vasodilators into EFC
  3. arterioles dilate
  4. decreased resistances creates increased blood flow
  5. O2 and nutrient supply to tissue increases as long as metabolism is increased
33
Q

reactive hyperaemia stages

A
  1. decreased tissue blood flow due to occlusion
  2. metabolic vasodilators accumulate in EFC
  3. arterioles dilate, but occlusion prevents blood flow
  4. remove occulusion
  5. decreased resistances creates increased blood flow
  6. as vasodilators wash away, arterioles constrict and blood flow returns to normal