physiology - general Flashcards

1
Q

what is motility

A

mechanical activity mostly involving smooth muscle (skeletal muscle is involved in mouth to upper oesophagus and anal sphincter)

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2
Q

what is digestion

A

chemical breakdown by enzymatic hydrolysis of cole foodstuffs to smaller, ABSORBABLE units

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3
Q

what is absorption

A

transfer of the absorbable products of digestion from the digestive tract to the blood or lymph

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4
Q

what does circular muscle contraction cause in the GI tract

A

lumen becomes narrower and longer

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5
Q

what does longitudinal muscle contraction cause in the GI tract

A

intestine becomes shorter and fatter

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6
Q

what does muscularis mucosa contraction cause in the GI tract

A

change in absorptive and secretory area of mucosa (mixing activity)

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7
Q

how many sphincters are there? name them

A
  1. upper oesophageal (UOS)
  2. Lower oesophageal (LOS)
  3. pyloric sphincter
  4. ileocaecal valve
  5. internal anal sphincter
  6. external anal sphincter
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8
Q

which sphincters are comprised of smooth muscle

A
Lower oesophageal (LOS) pyloric sphincter
ileocaecal valve
internal anal sphincter
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9
Q

which sphincters are comprised of skeletal muscle

A
upper oesophageal (UOS)
external anal sphincter
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10
Q

what are the organs associated with the alimentary canal

A

mouth and oropharynx
oesophagus
stomach
small intestine (duodenum, jejunum, ileum)
large intestine (caecum, appendix, colon)
rectum and anus

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11
Q

what are the accessory structures associated with the alimentary canal

A

salivary glands
pancreas
liver and gall bladder

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12
Q

what are the major motility patterns in the GI tract (5)

A
peristalsis
segmentation
colonic mass movement 
migrating motor complex 
tonic contractions
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13
Q

what is peristalsis

A

a wave of relaxation followed by contraction that normally proceeds along the gut in an aboral direction

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14
Q

what triggers peristalsis

A

distension of the gut wall

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15
Q

what is tonic contractions

A

sustained contractions
low pressure = organs with major storage function (e.g stomach)
high pressure = sphincters

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16
Q

what is migrating motor complex

A

powerful sweeping contractions from stomach to terminal ileum

17
Q

what is colonic mass movement

A

powerful sweeping contraction that forces faeces into the rectum

18
Q

what is segmentation

A

(mixing/churning)

rhythmic contractions of the circular muscle layer that mix and divide luminal contents

19
Q

stimulation of the parasympathetic innervation of the GI tract causes what

A

increased gastric, pancreatic and small intestinal secretion
increased blood flow
increased smooth muscle contraction

20
Q

inhibition of the parasympathetic innervation of the GI tract causes what

A

relaxation of some sphincters

receptive relation of the stomach

21
Q

stimulation of the sympathetic innervation of the GI tract causes what

A

increased sphincter tone

22
Q

inhibition of the sympathetic innervation of the GI tract causes what

A

decreased motility
decreased secretion
decreased blood flow

23
Q

who does electrical activity occur in the stomach, small and large intestine

A

slow waves

detailed: rhythmic patterns of membrane depolarisation and repolarisation that spreads from cell to cell via gap junctions

24
Q

what does the slow wave electrical activity determine

A

max frequency, direction and velocity of rhythmic contractions

basic electrical rhythm (BER)

25
what is the slow wave electrical activity driven by
interstitial cells of cajal (ICCs) | pacemaker cells are also interspersed between the smooth muscle cells
26
when would contraction occur (in relation to slow wave)
if the slow wave amplitude is sufficient to trigger SMC AP
27
where is the enteric nervous system (ENS) located within the GI system
myenteric (Auerbach's) plexus | submucous (Meissner's) plexus
28
where is the enteric nervous system (ENS) located within the GI tissue
intrinsic