Physiology-Ascending Pathways Flashcards
Where is conscious sensation transmitted to?
Cerebral cortex
Where is unconscious proprioception transmitted to?
Cerebellum
All pathways for conscious sensation will have at least what 3 neurons?
Primary neuron: Cell body in DRG, Secondary neuron: Cell body in spinal cord or brainstem, Tertiary neuron: cell body is in the thalamus and projects into the primary somatosensory cortex
The axon of which neuron is typically the one that will decussate to the opposite of the CNS in the spinal cord or brainstem?
Secondary neuron
Where do axons conveying conscious sensation terminate at?
Thalamus
What are the three types of somatic receptors?
Mechanoreceptors, nociceptors and thermoreceptors
How do the different sensory neuron fibers differ in each of these categories: diameter, myelination, receptors, sensory modality and fiber tract?
*

What type of nerve root damage would be required to loose sensation in an entire dermatome?
Damage to 3 sequential nerve roots. This is because there is significant overlap between dermatomes.
What sensory neuron fibers enter the zone of Lissauer and what fibers do not?
Large (A-alpha/Group 1a/1b) and Intermediate (A-beta/Group III) avoid the gray matter and travel up the white matter in the spinal cord. Small, thinly myelinated (A-delta/Group III) and unmyelinated (C/Group IV) enter the zone of Lissauer and synapse in the spinal cord gray matter.

What is a fasciculus?
A bundle of axons with a common origin and termination in the CNS
What are the four ascending somatosensory tracts?
*

Describe the characteristics of each category indicated below in the posterior column (lemniscal) ascending system:

*

Where do the primary afferent fibers travel from the lower thoracic, lumbar and sacral regions in regard to fasciculus gracilis?
The sacral axons enter first and are most medial. The lower thoracic axons (T7 and below) enter last and are most later. The lumbar axons are sandwiched between the two.

What is the posterior funiculus include at T6 and above? Below T6?
T6 and above = Fasciculus gracilis + fasciculus cuneatus. Below T6 = Fasciculus gracilis

Where do the primary afferent fibers travel from the upper thoracic, lower cervical and upper cervical regions in regard to fasciculus cuneatus?
Upper thoracics enter 1st and are most medial. Upper cervicals enter last and are most later. Lower cervicals are between the two.

Where do the posterior column fibers running in fasciculus gracilis end up synapsing?
Nucleus gracilis in the medulla.
Where do the posterior column fibers running in the fasciculus cuneus end up synapsing?
Nucleus cuneus in the medulla.
You feel how soft your baby’s head is. The sensory touch stimulus travels up to the DRG, synapses, goes through the posterior column ascending system and into the medulla. At this point the fibers cross. What fibers cross and where do they land?
The primary axon synapses on the secondary neuron in the medulla. Secondary axons (internal arcuate fibers) which cross over and land in the medial lemniscus.

Who is the headless man standing?
Medial lemniscus. Fibers from the nucleus gracilis and nucleus cuneus land here and transmit posterior column sensory information for all body parts except for the head.
What happens to the orientation of the posterior column fibers in the medial lemniscus as you move from the medulla to the basilar pons?
The man “slips out on his feet” with the lower fibers lateral and upper fibers more medial.

Where do the secondary axons of the posterior column ascending system synapse after they travel through the pons? Where do the tertiary axons travel to?
Thalamus (ventral posterolateral nucleus). The tertiary axons travel to the primary somatosensory cortex and form the homunculus.

How is the homunculus organized in the primary somatosensory cortex?
Head, hands, arm, legs, genetilia.
Describe the characteristics of each category indicated below in the ascending anterolateral spinothalamic system (ALSTS):

*

Where do the secondary axons cross over in the anterolateral spinothalamic system (ALSTS)?
They start in the Zone of Lissauer and cross over through the anterior white commissure in the spinal cord.


















