physiology Flashcards
what occurs when local electrical change triggers a wave of excitation that travels along the muscle fiber
conductivity
what is the capability of being stretched between contractions
extensibility
how does muscle attach to bone
via tendons
what is connective tissue around muscle cells
endomysium
what is connective tissue around muscle fascicles
perimysium
what is connective tissue surrounding entire muscle
epimysium
where does regulation of calcium for muscle fibers occur
sarcoplasmic reticulum
what is the plasma membrane of a muscle fiber
sarcolemma
what is the cytoplasm of a muscle fiber
sarcoplasm
what is the filamentous proteins which provide structure and contractile capacity to muscle
myofilaments
what are large intracellular bundles of contractile protein myofilaments
myofibrils
what are the tubular invaginations of the sarcolemma which penetrate through the cell and emerge on the other side; essential for calcium release from cisternae
transverse tubules
what is the thick filament primary made of
myosin
what is the thin filament mostly made of
actin
describe the protein of myosin
it is a hexametric protein, composed of 2 heavy chain polypeptides and 4 light-chain polypeptides
what are the 3 functions of the myosin sub fragment-1(S-1)
attachment site for actin to form actomyosin linkages (cross bridges), binding site for adenosine nucleotides, ATPase enzymatic region for hydrolysis of ATP