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Obstetrics > Physiological Changes in Pregnancy > Flashcards

Physiological Changes in Pregnancy Flashcards

1
Q

What happens to oestrogen?

A

Rises - produced by placenta

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2
Q

What happens to progesterone?

A

Rises - produced by placenta

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3
Q

What happens to thyroid hormones?

A

Rise in T3+4 - due to increase in thyroid-binding globulin

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4
Q

What happens to the anterior pituitary hormones?

A

Rise in

  • ACTH
  • Prolactin
  • MSH
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5
Q

What does the rise in MSH cause?

A

MSH = melanocyte stimulating hormone

Linea nigra - line down stomach

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6
Q

What happens to cortisol?

A

Rises

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7
Q

What happens to aldosterone?

A

Rises

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8
Q

What happens to insulin?

A

Insulin resistance increases - more insulin needs to be produced

Due to rises in prolactin + cortisol

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9
Q

What happens to LH + FSH?

A

Fall - suppressed by prolactin

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10
Q

What happens to blood volume?

A

Increases - due to RAAS activation

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11
Q

What happens to TPR?

A

Falls - due to progesterone

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12
Q

What happens to BP?

A

Falls

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13
Q

What happens to CO?

A

Rises

Increase in stroke volume + HR

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14
Q

What happens to the respiratory system?

A

Increase in tidal volume and RR

In order to meet increasing fetal oxygen demands

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15
Q

What happens to the GI system?

A

Upwards displacement of stomach - causes increased pressure = reflux

Smooth muscle relaxation - due to progesterone = constipation

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16
Q

What happens to the renal system?

A

Increased blood flow to kidneys = increased GFR

Increased aldosterone = salt + water retention

Dilatation of ureters = urinary stasis

17
Q

What happens to fibrinogen + clotting factors?

A

Increase - leads to hypercoagulable state

Increases VTE risk

18
Q

What happens to plasma volume?

A

Increases

19
Q

What is the effect of plasma volume increase?

A

Dilutional effect on RBCs

Increases risk of anaemia

20
Q

What happens to ALP?

A

Increases - due to placental secretion

Obstetrics (40 decks)

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