Down Syndrome Screening Flashcards
Which tests can be done for Down syndrome screening?
Combined test
Quadruple test
When is the combined test done?
11-14 weeks
What happens in the combined test?
USS - measure nuchal translucency
Maternal bloods
- B-HCG
- PAPPA
What should nuchal translucency be?
<6mm
What result of B-HCG indicates a higher risk?
Raised
What result of PAPPA indicated a higher risk?
Low
What happens in the quadruple test?
B-HCG
AFP
Serum oestriol
Inhibin A
When is the quadruple test offered?
14-20 weeks
What result of AFP indicates a higher risk?
Low
What result of serum oestriol indicates a higher risk?
Low
What result of inhibin A indicates a higher risk?
Raised
What other test can be performed privately?
NIPT
Tests for fetal DNA in mothers blood
When is a pregnancy considered high risk for Down syndrome?
Risk < 1 in 150
What other tests are offered if high risk for Down syndrome?
Chorionic villus sampling
Amniocentesis
