Phosphoglucase Isomerase: Glycolysis Step 2 Flashcards
1
Q
What reaction does phosphoglucase isomerase (PGI) catalyze?
A
The isomerization of G6P to fructose 6-phosphate (F6P).
2
Q
What does the open-chain form of glucose have at carbon 1?
A
An aldehyde group
3
Q
What does the open-chain form of fructose have at carbon 1?
A
A ketone group
4
Q
Why is the isomerization of G6P to F6P a significant step in glycolysis?
A
Fructose 6-phosphate is readily cleaved into three-carbon units (unlike G6P).
5
Q
What change in functional groups occurs in the glycolysis reaction catalyzed by PGI?
A
The aldose of G6P is converted to the ketose of F6P.
6
Q
True or false: The isomerization of G6P to F6P requires the ring to open, then isomerize, then close again.
A
True
