Glyceraldehyde 3-Phosphate Dehydrogenase: Step 5 of Glycolysis Flashcards
1
Q
What reaction does GAPDH (glyceraldehyde-3-phosphate dehydrogenase) catalyze?
A
The oxidation and phosphorylation of GAP (glyceraldehyde 3-phosphate) by NAD+ and Pi to 1,3-bisphosphoglycerate (1, 3-BPG)
2
Q
True or false: The oxidation of GAP to 1,3-BPG is exergonic.
A
False
3
Q
What drives the endergonic reaction of GAP to 1,3-BPG that is catalyzed by GAPDH?
A
The exergonic reaction that it is coupled to and that follows it (1,3-BPG to 3-Phosphoglycerate)
4
Q
What does GAPDH stand for?
A
Glyceraldehyde-3-phosphate dehydrogenase
5
Q
What does 1,3-BPG stand for?
A
1,3-bisphosphoglycerate
6
Q
True or false: The oxidation and phosphorylation of GAP to 1, 3 BPG is irreversible.
A
False
