Pharmacology Addictive Substances (6.3) Flashcards
The following are symptoms of:
anxiolysis, disinhibition, slurred speech, ataxia, stupor, respiratory suppression, coma, death
Alcohol or benzo/ barbituate intoxication
How do you treat alcohol intoxication?
Support, restraint, protect airway, ventilate
The following are symptoms of:
agitation, insomnia, tremor, GI upset, increase pulse, seizures, hallucinations, delerium, death
Alcohol or Benzo/ barbituate withdrawal
When do symptoms of alcohol withdrawal begin?
8 hours after last drink
When do alcohol withdrawal symptoms peak?
24 hours
How do you treat benzo/ barbiturate intoxication?
Support, restraint, protect airway, ventilate
Benzo can be reversed with flumazenil
How do you treat withdrawal from benzo/ barbiturates?
Treat with benzo replacement until vital signs and withdrawal symptoms normalize
How do stimulants work?
Block dopamine reuptake
The following are symptoms of:
elevated mood and esteem, irritability, insomna, appetite loss, dilated pupils, racing heart, increase BP, hyperreflexia, psychosis, cardiac arrest, seizure
intoxication of stimulants
The following are symptoms of:
fatigue, anhedonia, depression, increased sleep, late onset insomnia, increased appetite
Withdrawal from stimulants
How do you treat stimulant intoxication and withdrawal?
Support, symptomatically
What receptors do opiates affect?
Mu–> reduces pain, increases positive emotion
Kappa/ Delta–> minld analgesia
How do Mu/ Kappa/ Delta receptors work?
G protein lined and cause hyperpolarization via cAMP reduction and increased K influx/ decreased Ca efflux
The following are symptoms of:
elevated mood, pupil constriction, respiratory suppression, gag reflex lost, low HR, constipation, low BP
opiate intoxication
The following are symptoms of:
restless, watery eyes, yawning, dilated pupils, good flesh, runny nose, increased HR, increased PB, GI distress and cramps, muscle cramps
opiate withdrawal
How is opiate intoxication treated?
support, protect airway
reverse with naloxone
How is opiate withdrawal treated?
Metahdone or buprenorphine
The following are symptoms of:
perceptual distortion, hallucinations, depersonalization, nystagmus, tremors, hyperreflexia, racing heart, flashbacks, paranoia
hallucinogens
How is hallucinogen intoxication treated?
supportive
The following are symptoms of:
elevated mood, expansive though, sedation, pupil constriction, red conjunctiva, increased appetite, panic, paranoia
cannibus intoxication
