Insomnia (1) Flashcards

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1
Q

Define dyssomnia

A

Sleep disorder characterized by problems in timing, quality, or amount of sleep

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2
Q

Define parasomnia

A

sleep disorder characterized by abnormalities in physiology or behavior associated with sleep

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3
Q

How does the DSM 5 define insomia?

A

Complaint of dissatisfaction with sleep quantity or quality associated with at least one of the followoing symptoms:

1- difficulty initiating sleep
2- difficulty maintaining sleep
3- early morning awakening w/ inability to return to sleep

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4
Q

How long/ how frequently must sleep disturbances occur to be considered insomnia?

A

3 nights per week and present for 3 months

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5
Q

T/F: If a sleep disturbance is attributable to the physiological effects of a substance or a coexisting medical or mental disorder it is considered insomnia

A

False…it is not considered insomnia

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6
Q

Name some endogenous causes of insomnia?

A

Excitatory neurotransmitters in excess at night

Inhibitory neurotransmitter deficiency at night

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7
Q

Where can excess excitatory neurotransmitters come from at night? What neurotransmitters are involved?

A

Locus ceruleus–> NE
Raphe nucleus–> serotonin
VTA–> dopamine
Tubomamillary nucleus–> Histaime

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8
Q

What can cause an inhibitory neurotransmitter deficiency at night?

A

loss of GABA tone, loss of melatonergic tone, loss of andenosinergic tone

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9
Q

What are some physical causes of insomnia?

A

CNS stimulants, withdrawal from sedating agents, and medical conditions (chronic pain, pulm disease)

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10
Q

What are some psychiatric causes of insomnia?

A

Major depressive disorder, bipolar disorder, generalized anxiety disorder

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11
Q

What are some effects of insomnia? (4)

A

1- decreased quality of life

2- complaints of impaired daytime performance/ more accidents/ absenteeism

3- self medication/ substance abuse

4- association with psychiatric disorders

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12
Q

What is step 1 in insomnia management?

A

Diagnose, informed consent, education

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13
Q

What is step 2 in insomnia management?

A

Behavioral counseling (sleep hygiene and stimulus control)

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14
Q

What is step 3 in insomnia management?

A

Sleep restriction therapy and cognitive/ behavioral therapy

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15
Q

What is step 4 in insomnia management?

A

Pharmacologic therapy

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16
Q

What are some OTC agents used to treat insomnia?

A

Melatonin

Antihistamines

17
Q

What are some Rx agents that are not habit forming medications for insomnia?

A

Antihistamines (doxepin)

Melatonin 1+2 agonists (ramelteon and tasmelteon)

18
Q

What are some Rx agents that are mildly habit forming medications for insomnia?

A

Benzodiazepine receptor agonists (zolpidem, zaleplon, ezopiclone)

Orexin 1 + 2 antagonists (suvorexant)

19
Q

What are some Rx agents that are habit forming medications for insomnia?

A

Benzodiazapines (trazolam, temazepam, flurazepam)

Off lable options (trazadone, queticipine)