pharmacology Flashcards

1
Q

side effects for digitalis

A

arrhythmias
palpations
fatigue
GI disturbances
visual disturbances
hyperkalemia
confusion
delirum

digoxin toxicity

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2
Q

examples of digitals

A

Digitoxin
Lanoxin

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3
Q

mechanism of digitalis medication

A

slows down HR but increases the strength of contraction
quanitity < quality
increases cardiac output

use for systolic dysfunction (EF<40%) in pts with CHF

fewer and better contractions/beats

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4
Q

antiarrhythmic drugs + antihypertensive drugs

A

beta blockers
ca channel blockers

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5
Q

only antihypertensive drugs

A

diuertics
ACE inhibitors
ARB blockers

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6
Q

beta blocker effects

A

decrease HR
decrease BP
bronchoconstriction

help with preload and reduce afterload

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7
Q

beta blocker side effects

A

othostatic hypotension
dizziness
lightheadesness
rining in the ears
venous pooling
bradycardia

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8
Q

who do you not use beta blockers with

A

asthma and COPD due to bronchoconstriction

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9
Q

ca channel blocker examples

A

“pines and zems”

amlodipine
verapamil
diltiazem

common: Norvasc and Nefidipne - Procardia XL

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10
Q

mechanism ca channel blockers

A

decrease HR
decrease BP

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10
Q

adverse effects of ca channel blockers

A

orthostatic hypotenion
dizziness
lightheadedness
ringing in ears
venous pooling

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11
Q

explain loop diuretics mechanism

A

preload and afterload decrease so its good for both L and R CHF patients

inhibits reabsoption of water and electrolytes from the loop of henle

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12
Q

side effects of looped diuretics

A

hypokalemia
hypocalemia
hypoatremia
dehydration
orthostatic hypotension
reflex tachycardia
dizziness
lethargy
dizziness

everything is lost

reflex tachycardia: dueto the decrease in BP, the heart is trying to compensate and therefore increases HR due to a reflex

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13
Q

explain potassium sparing dieretics

A

ex: sprionolactone and aldoctone

keeps potassium in

side effects:
hyperkalemia
gynescomastia (breast tissue in males)
hypocalemia
hypoatremia
dehydration
orthostatic hypotension
reflex tachycardia
dizziness
lethargy
dizziness

same effects as diuretics but whats different is hyperkalemia and gynescomastia

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14
Q

explain thiazides

A

“CLUG”
hyperCALCEMIA
hyperLIPEDEMA
hyperURECEMIA
hyperGLYCEMIA

should be avoided with elderly, DM and renal dysfn=unction

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15
Q

what do ACE inhibitors do

A

reduced BP by blocking ACE enzyme

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16
Q

side effects of ACE inhibitors

A

orthostatic hypotension
hyponatremia
hyperkalemia
DRY HACKING COUGH

decreased taste perception
angioedema
dehydration

should not be comined with looped diuretics due to hyperkalemia side effects

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17
Q

examples of ARB blockers

A

“sartans”

losartan
telmisarten
candesartan

18
Q

when would a patient be prescribed ARB blockers

A

when they are intolerant to ACE inhibitors (may have a dry hacking cough)

only given orally

19
Q
A
20
Q

side effects of ARB blockers

A

hypotension
dizziness
lightheadedness
fatigue
HYPERKALEMIA

21
Q

Examples of ACE inhibitors

A

“prils”

captopril
enalapril
lisinopril

22
Q

how do nitrate work

A

vasodilation of aterial and venous vessels

used for angina pectoris - stable or variant

given sublingually, 3 doses every 5 minutes

it significantly drops BP therefore they need to be sitting or lying down before taking a dose

side effects:
dizziness
lightheadedness
orthostatic hypotension
HA
flushing
reflex tachycardia
venous pooling

does not work for unstable angina. call 911

23
Q

what do nitrates do with preload and afterload

A

it decreases

24
Q

examples of blood thinners

A

warfarin
coumadin
heparin

25
Q

examples of blood thinner categories

A

anticoagulants
antiplatelets

26
Q

side effects for anticoagulants

A

bleeding
easy bruising
hemorrahge hemarthrosis
light headedness

27
Q

INR values

A

health: 0.9-1.1 seconds

if someone is on anticoagulants: 2-3 seconds

28
Q

examples of antiplatelets

A

aspirin
clopidogrel

29
Q

side effects antiplatelets

A

peptic ulcers
gastritis
risk of internal bleeding

30
Q

why would someone be on antiplatelets

A

prevent stroke and MI

31
Q

what do NSAIDs do

A

anti inflammatroy
antipyretic
analgesic

32
Q

side effects of NSAIDS

A

gastric ulcers
bleeding
n/v

33
Q

explain acetaminophen

A

ex: tylenol

block the sensation of pain, HA

NOT ANTI INFLAMMATORY

no acute side effects. only liver damage

34
Q

opioid pain relievers

A

methadone, fentanyl, hydrocodone, oxycodone, morphine

side effects: respiratory and CNS depression, bradycardia, constipation, slowed breathing, dizziness, drowsiness, slowness, addiction, tolerance

take medication 30 min prior to PT

35
Q

types of benzodiazepines

A

diazepam (valium)
clonazepam (klonopin)
alprazolam (xanax)

36
Q

what type of medication is prescribed for reduction mm spasms/myofascial pain sydnrome

A

cyclobenzaprine (flexeril)

37
Q

use of baclofen

A

works CNS

to reduce mm spasticity seeen with spinal cords lesion - MS, SCI, vs cerebrals lesions

38
Q

side effects of baclofen

A

hypotonia
confusion
hallucination
nausea
dizziness
increased risk of falls
drowsiness
shallow breathing

39
Q

how does botox works

A

blocks acetylocholine

mm spasticity seen with CP

40
Q

side effects of corticosteroids

A

osteoporosis
cushing syndrome (adrenal gland)
delyed wound healing

41
Q

side effects of bronchodilator drugs

A

tremors
palpatation (inc HR)
GI disturbances
dry mouth

42
Q

which of the following drugs would not be used to lower blood pressure in hypertensive patients
- thiazide diuretics
- ACE inhibitos
- Ca channel blockers
- digitalis

A
  • digitalis
43
Q

differences between beta blockers and ca channel blockers

A

bb: cause bradycardia and works as a bronchoconstrictor. not safe to give to COPD/asthma patients

ca channel blockers: safe to give to COPD/asthma due to them not acting as a bronchoconstrictor