Pharmacology Flashcards
is any chemical used for therapeutic purposes such as treating illness, relieving symptoms or conducting diagnostic testing
drugs
is a theoretical concept that a drug would have all good effects and qualities and no negative effects or qualities
ideal drug
combined effect of medications taken together
drug interaction
when two or more drugs are prescribed together
drug-drug
food in stomach can significantly change the absorption of drugs
nutrient-drug
when some drugs used to treat a disease, can cause exacerbation in or interfere with another disorder that a patient may have at the same time
disease-drug
refers to all of the names by which a drug can be identified
drug nomenclature
is usually long name of the chemical composition of the druge
chemical name
Where can the chemical name be found
package insert
To whom is the chemical name is important
FDA, offices that register patent on the drug, and chemist and scientist working in pharmaceutical fields
another name for generic name
nonproprietary and approved name
what is the official medical name assigned by the producer
generic or nonpropritary name
What is the USP-NF book
book of public standards related to pharmacology
Brand name
known as trade or proprietary name
What is brand name
is given to a drug by manufacturer, meaning the manufacturer owns the drug
For example what is the generic name for the Brand name Tylenol
acetaminophen
Generic name of LIpitor
Atorvastatin
Brand Name Nexium
esomeprazole
Brand name Glucophage
Metformin
After scientist develop and test new drugs, what is its fist name
Chemical name
What does the manufacturer market the drug as after the FDA approves the drug
Brand name
Which is the shorter name of a drug
Brand names are usually shorter than generic name
Why are Brand Names for drugs shorter?
so consumers can remember them
What does the “R” mean on the product label
that the drug has been registered by the U.S. Patent and Trademark Offic
What does “TM” mean
trademark
How long does the pharmaceutical co hold the patent for a new brand name drug
about 20 years after its discovery
when can other co create generic versions of the drug
after the time for sole rights has expired 11-12 years
is the government agency that decides what drugs may be sold and under what legal restriction.
Food and Drug Admin
what is a legal term, that means that the FDA has no restrictions on the drug
Over the Counter OTC
what are drugs that can only be distributed by prescriptions bc of harmful side effects if not used with caution
Legend drug
What drugs that are dangerous and subject to abuse, therfor only acceptable medical usages and under rugid rules
controlled substances
regulates the manufacture and sale of dangerous drugs such as narcotis
DEA drug enforcement admin
study of movement of drugs via the body
pharmacokinetics
study of drugs, and their interactions on living systems
pharmacology
understanding of the structures in the body
anatomy
understanding of what happens to the body when its not fuctionally normally due to illness or injury
pathology
understanding the chemical composition of medications and how they interact with the body
chemistry
is important due to how patients perceive their health status and understand the health education being provided
psychology
person who dispenses drugs at a pharmacy
pharmacist
scientist who studies all aspects of drugs including origins, functions, chemistry, effects and uses
pharmacologist
study of new drug synthesis
medicinal chemistry
study of drug action, effects on body
pharmacodynamis
study of the movement of drugs in the body
pharmacokinetics
study of interaction of drugs with molecules such as DNA, RNA, and enzymes
molecular pharmacology
treatment of disease with therapeutic meds
pharmacotherapeutics
study of poisons
toxicology
substances that change physiological processes in the body
drugs
where can drugs be derived from
plants, animals or minerals
naturally occurring substances
minerals
substances missing from the human body may be found in the body tissues of?
animals
can be derived from pancreas of cows or hogs
insulin
duplicate the desired properiies of natural susbtances
synthetic drugs
most common synthetic drugs
aspirin
fastest growing areas in pharmacological studies
recombinant DNA tech
what does recombinant DNA tech uses
artificially manipulated DNA segments from diff organic sources
What are the four processes involved in pharmacokinetics (movement of drugs in body)?
absorption, distribution, metabolism, and excretion
refers to the movement of a drug from its site of admin into blood
absorption
movement of a drug from blood into tissues and cells
distribution
involves physical and chemical alteration of drug in the body
metabolism
refers to removal of the waste products of drug metabolism from the body
excretion
what are the primary sites of absorption
mucosa of mouth, lungs, stomach gastro and small intestine, rectum, and blood vessels in muscle tissue
what are the factors that influence absorption rate
administration, drug ph, food, location, topical, and inhalation
what type of administration of the drug can influence absorption rate
incorrect administration
what does food in stomach do to the rate of absorption
usually help decrease stomach irritation from meds and slow rate of absorption
What does an empty stomach do to rate of absorption
increate rate of absorption but increase stomach irritation by meds
Where are meds that are absorbed in fats and lipids absorbed at
gastrointestinal tract
where are a meds that are alcohol base more easily absorbed
routes other than oral
amount of drug circulating in the blood stream
drug blood level
protects the brain by restricting entry of water soluble electrolytes
blood brain barrier
can pass into the brain and cerebrospinal fluid
lipid soluble drugs
barrier that isnt as restrictive as the blood brain barrier
placental membrane
what can cross the placental membrane barrier
water and lipid soluble drugs