Pharmacokinetics Flashcards
A medicine …
May contain one or more drugs and contains additives
Match the term with the correct definition:
Enteral and patenteral
Enteral = via the gut Parenteral = avoids the gut
Cytochrome P450 is a …
Liver enzyme
Drugs that are highly bound to plasma proteins require …
A higher loading dose
Factors influencing drug absorption in the gut include …
The pH of the gastrointestinal tract, food and drink and stomach motility
Lipid soluble drugs are removed temporarily from the circulation by …
Adipose tissue
Pharmacokinetics explains …
The distribution of a drug around the body and how the body deals with drugs
Plasma binding is the extent to which the drug binds with …
Plasma protein
What factors affect pharmacokinetics?
Site of administration, plasma protein binding and rate of absorption
The first pass effect is …
The amount of a drug that is removed from the hepatic portal vein by the liver
