Pharmacodynamics

Question 0

Match the correct features with the terms below:
Drugs with high affinity, drugs with high intrinsic activity, drugs with no intrinsic activity, mimic the effect of resident natural ligand, receptor binding results in no effect, drugs with low affinity

Answer 0

Drugs with high affinity = agonist
Drugs with high intrinsic activity = agonist
Drugs with no intrinsic activity = antagonist
Mimic the effect of resident natural ligand = agonist
Receptor binding results in no effect = antagonist
Drugs with low affinity = antagonist

Question 1

Match the correct features with the terms below:

Partial agonist, non-competitive antagonist and competitive antagonist

Answer 1

Partial = act on receptor but without maximum effect
Non-competitive = doesn't bind directly with receptor but still incapacitate the receptor
Competitive = compete for the same receptor or as an agonist

Question 2

What are employed by the endocrine system to communicate with cells and tissues?

Answer 2

Adrenaline, hormones and bloodstream

Question 3

Pharmacodynamics is the science/study of…

Answer 3

The effect of a drug on the body

Question 4

Receptors are composed of …

Answer 4

Protein

Question 5

What are the potential cellular sites of action for a drug?

Answer 5

Receptors, enzymes and ion channels

Question 6

The anaesthetic lidocaine …

Answer 6

Reduces sodium entry into cells

Question 7

What are employed by the nervous system to communicate with cells and tissues?

Answer 7

Noradrenaline, neurones, acetylcholine and dopamine

Question 8

What is a first messenger?

Answer 8

Neurochemicals

Question 9

What is a second messenger?

Answer 9

Enzymes, calcium ions and lipids