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GM 2 > Pharm- Diarrhea & Antispasmotic > Flashcards

Pharm- Diarrhea & Antispasmotic Flashcards

1
Q

Metoclopramide- Indications

A

Antiemetic- chemotherapy

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2
Q

Metoclopramide- MOA

A

Dopamine receptor antagonist. Stimulates GI tract motility

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3
Q

Metoclopramide- AE

A

Sedation, diarrhea, extrapyramidal symptom

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4
Q

Dicyclomine- MOA

A

Anticholinergic- relaxes smooth muscle, inhibits bradykinin and histamine

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5
Q

Dicyclomine- Indications

A

IBS- antimotility agent

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6
Q

Dicyclomine- AE

A

Dry mouth, dizziness, blurred vision, psychosis, hallucination

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7
Q

Hyocyamine- MOA

A

Anticholinergiic- antagonizes acetylcholine

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8
Q

Hyocyamine- Indications

A

IBS, antispasmotic on smooth muscle

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9
Q

Hyocyamine- AE

A

Dry mouth, eyes, urinary retention, anaphylaxis

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10
Q

Antiparistaltic agents- MOA

A

Activate opioid receptors in enteric NS, decreaseing paristalsis and inhibiting acetylcholine

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11
Q

Antiparistaltic agents- Indications

A

Diarrhea control

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12
Q

Antiparistaltic agents-AE

A

Drowsiness, abd. Cramps, dizziness

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13
Q

Adsorbents- Indications

A

Diarrheal control, least effective

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14
Q

Adsorbents- MOA

A

Adsorb toxins & microorgs, coat and protect intestinal mucosa

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15
Q

Adsorbents- AE

A

Impaired absorption of other drugs

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16
Q

Bismuth subsalicylate- MOA

A

Decreases fluid secretion in bowel,

17
Q

Bismuth subsalicylate- Indications

A

Travellers diarrhea,

18
Q

Bismuth subsalicylate- AE

A

Black tongue & stools

19
Q

Polycarbophil- MOA

A

Bulk laxative

20
Q

Polycarbophil- Indications

A

Promotes regularity, relives constipation

21
Q

Polycarbophil- AE

A

GI obstruction, bleeding, abd pain & distension

22
Q

Bile acid sequestrants- MOA

A

Bind to bile acids, increasing excretion in feces

23
Q

Bile acid sequestrants-Indications

A

Diarrhea associated with excess fecal bile acid

24
Q

Bile acid sequestrants- AE

A

Constipation, flatulence, inpaired absorption

GM 2 (15 decks)

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