Colorectal disorders Flashcards

1
Q

Ulcerative collitis- Sx

A
  • Rectal bleeding, bloody diarrhea
  • Bright red blood
  • Tenesmus
  • Abd cramping
  • Fever & sweats
  • Friability, erosion, pseudopolyps
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2
Q

Ulcerative collitis- Eti

A
  • Inflammation of colon only
  • Idiopathic
  • Periods of symptomatic flare ups
  • Nonsmokers
  • Appendectomy before 20 increased risk
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3
Q

Chrons disease- Eti

A
  • Any portion of GI tract- mouth to anus
  • Anus may be spared
  • Smokers
  • 40% ilium + colon
  • Terminal ilium most commonly involved
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4
Q

Chrons disease- Sx

A
  • Diarrhea
  • ABd pain & RLQ tenderness or mass
  • Wt. loss
  • Fever & night sweats
  • Iron deficiency anemia
  • Obstructive symptoms- N/V postprandial pain
  • Fistulations
  • Arthralgials, pyoderma, erythema nodosum, gallstones
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5
Q

Chrons disease- Dx

A
  • Biopsy/ pathology report
  • CT scan- evaluation of small bowel
  • Stool studies
    Endoscopy: Normal mucosa next to abnormal:
  • Stellate ulcer
  • Skip lesion
  • Cobblestoning
  • Deep linear ulcers
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6
Q

Irritable Bowel Syndrome- Eti

A
  • Late teens- 20s
  • W>M
  • Common functional bowel disorder
  • Idiopatic
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7
Q

Irritable Bowel Syndrome- Sx

A
  • Sx > 3 months
  • Subjective distension
  • Abd pain, intermittent, crampy, relieved by deification
  • Alternating constipation & diarrhea
  • Normal phys exam
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8
Q

Irritable Bowel Syndrome- Dx

A
  • Dx of exclusion- rule out cancer, celiac, parasite, etc
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9
Q

Irritable Bowel Syndrome- Tx

A
  • Antispasmodics or antidiarrheals
  • Fiber
  • Antidepressants
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10
Q

Ulcerative colitis- Dx

A
  • Sigmoidoscopy

- Abd radiograph for toxic megacolon

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11
Q

Ulcerative colitis- Tx

A
  • Biologics
  • Corticosteroids
  • Antibiotics
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12
Q

Toxic megacolon- Eti

A

Complication of UC in <2% of patients

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13
Q

Toxic megacolon- Sx

A

Colonic dilations > 6cm with signs of toxicity

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14
Q

Toxic megacolon- Dx

A

Abd radiograph

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15
Q

Toxic megacolon- Tx

A

Broad spectrum abx

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16
Q

Diverticulosis- Eti

A
  • Increased in western societies & age

- Diet, marfan, scleroderma

17
Q

Diverticulosis- Sx

A
  • Normal physical exam

- Nonspecific complaints- constipation, abd pain, fluctuating bowel habits

18
Q

Diverticulosis- Dx

A
  • Barium enema & CT imaging
19
Q

Diverticulosis- Tx

A

High fiber diet & fiber supplements

20
Q

Diverticulitis- Eti

A
  • 25% pts > 40
  • Increases with age
  • 10-20% patient with diverticulosis
21
Q

Diverticulitis- Sx

A
  • LLQ aching abd pain
  • Constipation or diarrhea
  • low grade fever
  • LLQ mass
  • N/V
22
Q

Diverticulitis- Dx

A
  • CT abd scan

- Colonoscopy contraindicated

23
Q

Diverticulitis- Tx

A
  • Clear liquid diet

- Broad spectrum abx

24
Q

Colorectal cancer- Eti

A
  • 2nd leading cause of death due to malignancy
  • 6% americans- 40% die
  • Personal/ fam hx
  • Most adenocarcinoma
  • Increased risk with age, blacks, red meat, IBD
25
Q

Colorectal cancer- Sx

A
  • Iron deficiency anemia
  • fatigue
  • abd pain
  • obstructive symptoms
  • Alternating constipation & diarrhea
26
Q

Colorectal cancer- Dx

A
  • Colonoscopy

- Staging- TNM

27
Q

Colorectal cancer- Tx

A
  • Stage II-III: Chemo

- Stage IV: Chemo, biologics, surgical excision

28
Q

Polyps- Eti

A
  • Cause of 95% of adenocarcinoma

- Present in 30% adults > 50

29
Q

Polyps- Sx

A
  • Occult blood loss & anemia
  • Ulceration -> hematochezia
  • Asymptomatic
30
Q

Polyps- Dx

A
  • Colonoscopy & biopsy

- FIT test

31
Q

Polyps- Tx

A
  • Polypectomy
32
Q

Polyposis- Eti

A
  • Inherited condition
  • 1:10,000
  • Develop at 15, CA by 40
  • Colorectal CA inevitable by 50
33
Q

Polyposis- Sx

A
  • Fam hx

- + genetic testing

34
Q

Polyposis- Dx

A
  • Genetic counseling/ testing

- endoscopy every 1-3 years

35
Q

Polyposis- Tx

A
  • Cox 2 inhibitors reduce number/ some
  • Surgery
  • Frequent sigmoidoscopy