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GM 2 > Pharm- Constipation > Flashcards

Pharm- Constipation Flashcards

1
Q

Stimulants- Indications

A
  • Opioid induced constipation

- Intermittent use

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2
Q

Stimulants- MOA

A
  • Stimulates peristalsis & evacuation of bowels within 8-10 hrs
  • Irritation of smooth muscle
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3
Q

Stimulants- AE

A

Laxative abuse, cathartic colon, nausea, abd distenstion and cramps

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4
Q

Bulk forming agents- MOA

A

Increase peristaltic activitiy through intestinal distension & H2O retention- softer stools

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5
Q

Bulk forming agents- Indications

A

Constipation & IBS

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6
Q

Bulk forming agents- AE

A

Intestinal obstruction, gas, bloating

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7
Q

Osmotic agents- Indications

A

OTC laxatives for constipation, bowel prep

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8
Q

Osmotic agents- MOA

A

Nonabsorbable salts which hold water in intestine via osmosis increases peristaltic activity

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9
Q

Osmotic agents- AE

A

Hypermagnesemia in renal failure, diarrhea, abd pain, safe for long term use.

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10
Q

Enema- Sodium phosphate- MOA

A

Saline which increases bowel distention increaseing parestalsis

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11
Q

Enema- Sodium phosphate- Indications

A

Colonic lavage for endoscopy

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12
Q

Enema- Sodium phosphate- AE

A

Electrolyte disturbances, abd distension, hypersensativity

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13
Q

Surfactant/ stool softener- MOA

A

Emulsify with stool to ease passage- lower surface tension, draw in water

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14
Q

Surfactant/ stool softener- Indications

A

Constipation & regularity, short term medications- opiods

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15
Q

Surfactant/ stool softener- AE

A

diarrhea, abd cramping, rash

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16
Q

Mineral lubricants- MOA

A

Lubricates GI tract, decreases colonic absorption

17
Q

Mineral lubricants- Indications

A

Hard stool constipation, fecal impaction

18
Q

Mineral lubricants- AE

A

Aspiration pneumonia, absorption with concomitant use with mineral oil

19
Q

Constipation- Definition

A
  • Straining, hard stools, incomplete evacuation, blockage with at least 25% of bowel movements
20
Q

Synthetic sugars- MOA

A

Stimulates colonic activity by drawing water into lumen

21
Q

Synthetic sugars- Indications

A

Hepatic encephalopathy

22
Q

Synthetic sugars- AE

A

Bloating

GM 2 (15 decks)

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