Pharm 1 - Δ-Δ, Poisoning Flashcards

1
Q

Delta-delta (delta gap)

A

ΔAG - ΔHCO3

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2
Q

Delta gap indicating concomitant non-AG metabolic acidosis

A

< -6

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3
Q

Delta gap indicating concomitant non-AG metabolic alkalosis

A

> 6

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4
Q

RSI med that can cause malignant hyperthermia

A

Succinylcholine

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5
Q

Rx for malignant hyperthermia

A

Dantrolene

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6
Q

Rx for cyanide (first-line)

A

Hydroxocobalamin

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7
Q

Drug type / mechanism of sarin

A

Anticholinergic

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8
Q

Rx for organophosphates

A

Pralidoxime

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9
Q

Mechanism of action of organophosphates

A

inhibition of acetylcholinesterase (CHOLINERGIC)

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10
Q

Symptoms of cholinergic toxicity

A

DUMBBELS (diarrhea, urination, miosis, bronchospasm, bradycardia, lacrimation, salivation)

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11
Q

Methylene blue treats

A

Methemoglobinemia (and vasoplegia)

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12
Q

Tx for ethylene glycol or methanol poisoning

A

Fomepizole and dialysis

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13
Q

Rx for cyanide (second-line)

A

sodium nitrite, sodium thiosulfate

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