Peripheral Venous Disease FINAL Flashcards
Venous thromboembolism (VTE) is a blood clot believed to form as a result of
Virchow’s triad
Factors contributing to Virchow’s triad
hypercoagulable state
circulatory stasis
vascular wall injury
Thrombus formation can lead to __________ __________ which is a life threatening complication.
pulmonary embolism
Thrombus that is associated with inflammation
thrombophlebitis
Enlarged, twisted and superficial veins that can occur in any part of the body; however, they are commonly observed in the lower extremities and in the esophagus
Varicose veins
Occurs secondary to incompetent valves in the deeper veins of the lower
extremities, which allows pooling of blood and dilation of the veins.
The veins’ inability to carry fluid and wastes from the lower extremities precipitates the development of swelling, skin color/texture changes, venous stasis ulcers, and in advanced cases, cellulitis.
venous insufficiency
Associated with deep leg pain of sudden onset, which occurs secondary to the occlusion.
A dull ache is more commonly associated with varicose veins. If the thrombus is large enough, it will cause pain. A tingling sensation is associated with an alteration in arterial blood flow.
Unilateral swelling
DVT
o stasis dermatitis (brown discoloration) along the ankles that extends up the calf relative to the level of insufficiency
o Edema
o Stasis ulcers (typically found around ankles)
Venous insufficiency
Risk factors for DVT (VTE)
-associated w/Virchow’s triad
-surgery: hip, TKR, open prostate
-HF
-immobility
-pregnancy/oral contraceptives
-active cancer
Risk factors for Venous insufficiency
-sitting or standing in one place for a long time
-obesity
-pregnancy
-thrombophlebitis
Risk factors for Varicose veins
-female, age >30, family hx
-occupations w/ lots of standing
-pregnancy
-obesity
-heart disease
D-dimer measures fibrin degradation products present in the blood produced from fibrinolysis. A positive test indicates that thrombus formation has possibly occurred. Is it specific?
D-dimer is not specific. It just tells us clotting is happening somewhere.
PVD Meds
Anticoagulants & prophylaxis
-unfractionated heparin, low-molecular weight heparin, enoxaparin, fondaparinux, warfarin
Thrombolytics & platelet inhibitors
-TPA
Enoxaparin (Lovenox) is administered subcutaneously and can cause
bruising
IVC filters are used to treat DVTs. What do they do?
Catches the clot. Blocks it from going up to the lungs.