Coronary artery disease (CAD)/Stable angina Flashcards
Major types of angina
Chronic stable angina
Prinzmetal’s angina
Microvascular angina
Unstable angina
-Episodic pain lasting 5-15 min
-Provoked by exertion
-Relieved by rest or nitro
chronic stable angina
-occurs primarily at rest
-triggered by smoking and increased levels of some substances (histamine, epinephrine)
-may occur n presence or absence of CAD
Prinzmetal’s angina
-more common in women
-triggered by activities of daily living
-treatment may include nitro
microvascular angina
-new onset angina
-chronic stable angina that increases in frequency, duration, and severity
-occurs at rest or w/ minimal exertion
-pain refractory w/ nitro
unstable angina
Usually occurs at points of turbulence (i.e. vessel bifurcations). As plaque increases, arterial lumen progressively narrows→ decreased blood flow to myocardium→ischemia
Atherosclerosis
Angina pectoris
chest pain
Sx of angina pectoris
o Pain symptoms vary - ranges from a vague, barely troublesome ache, bloating, gas to a crushing sensation. Common beneath the sternum, may radiate to L shoulder, down the left arm, straight through to the back, into the throat, jaw, teeth.
o Women may have atypical symptoms such as malaise, SOB, Anxiety & Fatigue
What is the #1 modifiable risk factor for CAD?
smoking
Bad cholesterol
LDL
Good cholesterol
HDL
Troponins indicate
heart tissue death
Lab parameters for CAD
Total cholesterol <200 mg/dL
LDL <100 mg/dL
HDL >40 mg/dL
Triglycerides <150 mg/dL
C-reactive protein <0.175 mg/L (inflammation marker, but not cardiac specific)
Homocysteine <17
Diagnostic tests for CAD
-ECG
-stress tests
-CT or PET scans
Types of stress tests
o Treadmill/Bike - Exercise to stress the heart and look for symptoms of decreased perfusion
o Pharmacologic Stress Test - Same concept, uses dobutamine (increases contractility) or dipyridamole (coronary artery dilator) to stress the heart