Allergies FINAL (study last) Flashcards
Also called atopic allergy, hay fever, most common type
1st exposure –> T lymphocytes tell B lymphocytes to create IgE specific to allergen –> Mast cells (tissue) basophils (blood stream) have IgE receptors with lots of IgE attached —> allergen binds to IgE –> causes degranulation (allergic cascade)
Patho of allergies
Allergies Type I
Hay fever, allergic asthma, anaphylaxis, angioedema
What causes allergies?
Excessive production of immunoglobulin E (IgE) antibody class
Allergens are contracted by
inhalation, ingestion, or injection
Symptoms of allergies
Sneezing, runny nose, & red, watery, itchy eyes
Can be seasonal
Are allergies genetic?
yes
Allergy labs
ABGs
Allergy diagnostics
Skin prick test (SPT), Intradermal skin test, Blood tests, Physician supervised challenge tests, Patch tests
Allergy Meds
- Supportive therapy – no nasal washing!
- Complementary and alternative therapy - vitamin C, zinc
- Steroids - Used for anti-inflammatory effect and act to decrease edema in the bronchial airways and decrease mucus secretion.
- leukotriene inhibitors – Montelukast (Singulair)
- Antihistamines – Diphenhydramine (Benadryl)
- Eye decongestants
- Decongestants – Avoid use of nasal decongestant sprays regularly because they can cause a rebound effect.
- Bronchodilators
- Anti-inflammatories
- Antipyretics
- Mast cell stabilizers
Allergy procedures
Immunotherapy- Allergy Shots: Subcutaneous injection of low amount of allergens, then gradual increased amount.
Allergy complications
Angioedema & Anaphylaxis can be fatal - Potential for airway obstruction as a result of mucosal swelling & anxiety as a result of cerebral hypoxia and threat of death.
Uticaria (hives)
Ace inhibitors can cause
Angioedema