Peripheral Nerve And Skeletal Muscle

Question 0

Hypertrophic neuropathy

Thin or absent myelin sheath below the knee

Answer 0

Hereditary motor and sensory neuropathy

Charcot Marie Tooth disease

Question 1

Perivenular and endoneurual infiltration by lymphocytes

Albuminocytologic dissociation in CSF

Answer 1

Guillain Barre syndrome

Question 2

MC form of diabetic neuropathy

Answer 2

Distal symmetric neuropathy

Question 3

Destruction of anterior horn cells

Panfascicular atrophy

Answer 3

Spinal muscular atrophy

Infantile motor neuron disease

Question 4

Muscle fibers replaced by fibrofatty tissues

Inc numbers of internalized nuclei

Answer 4

DMD

BMD

Question 5

Gower sign

Calf pseudohypertrophy

Answer 5

Muscular dystrophies

Question 6

Subsarcolemmal band of cytoplasm
Irregular sarcoplasmic mass
Intrafusal fiber splitting

Answer 6

Ring fiber

Myotonic dystrophy

Question 7

Sustained involuntary muscle contractions

CTG

Answer 7

Myotonic dystrophy

Question 8

Irregular fiber with subsarcolemmal mitochondrial collections
Alterations in structure of cristae

Answer 8

Ragged red fibers
Parking lot inclusions

Mitochondrial myopathies

Question 9

Heliotrope rash on eyelids with periorbital edema
Dusky red patches over knuckles, elbows and knees
PROXIMAL muscle weakness
Perifascicular atrophy

Answer 9

Gottron lesions

Dermatomyositis

Question 10

Symmetric PROXIMAL muscle weakness

Panfascicular atrophy

Answer 10

Polymyositis

Question 11

Asymmetric DISTAL muscle weakness

Inclusion bodies in rimmed vacuoles

Answer 11

Inclusion body myositis

Question 12

Type 2 fiber atrophy

Immune complex deposits over postsynaptic membrane

Answer 12

Myasthenia gravis