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Pathology 2 > Neoplasia > Flashcards

Neoplasia Flashcards

0
Q

Non neoplastic tissue in a foreign location

A

Choristoma

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1
Q

Non neoplastic overgrowth of disorganized tissue indigenous to a particular site

A

Hamartoma

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2
Q

Genes involved in the normal growth and repair. Mutations can cause sustained activity of the genes

A

Proto oncogenes

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3
Q

Mutations can cause unregulated cell proliferation

Two cell hit hypothesis

A

Tumor suppressor genes

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4
Q

Degree of differentiation of neoplasia

A

Tumor grade

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5
Q

Degree of localization/spread

A

Tumor stage

More prognostic value

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6
Q

Cancers in children

A

ALL > CNS tumors > Burkitt’s lymphoma

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7
Q

Cancers in men

A

Prostate > lung > colorectal

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8
Q

Cancers in women

A

Breast > lung > colorectal

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9
Q

Cancer mortality in men

A

Lung > prostate > colorectal

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10
Q

Cancer mortality in women

A

Lung > breast > colorectal

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11
Q

Paraneoplastic syndromes

Cushing syndrome

A

Small cell carcinoma of the lung

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12
Q

Paraneoplastic syndromes

SIADH

A

Small cell carcinoma of the lung

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13
Q

Paraneoplastic syndromes

Squamous cell carcinoma

A

Hypercalcemia

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14
Q

Paraneoplastic syndromes

Hypoglycemia

A

Ovarian carcinoma

Fibrosarcoma

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15
Q

Paraneoplastic syndromes

Carcinoid syndrome

A

HCC
Bronchial adenoma
Pancreatic carcinoma

16
Q

Paraneoplastic syndromes

Polycythemia

A

Gastric and renal carcinoma

Cerebellar hemangioma

17
Q

Trousseau syndrome

A

Pancreatic carcinoma

18
Q

Lambert Eaton syndrome

A

Lung carcinoma

19
Q

Red cell aplasia

A

Thymoma

20
Q

Nephrotic syndrome

A

Hodgkin’s lymphoma

21
Q

Tumor Lysis Syndrome

A

Hyperkalemia
Hyperphosphatemia
Hyperuricemia
hypocalcemia

22
Q

Brain Metastases

A 
Lots of Bad Stuff Kill Glia
Lung
Breast
Skin melanoma
Kidney renal cell ca
GI
23
Q

Liver Mets

A 
Cancer Sometimes Penetrates Benign Liver
Colon
Stomach
Pancreas
Breast
Lung
24
Q

Bone Mets

A 
PurPLe Tinged Barney Loves Tasty Kids
Prostate
Thyroid follicular
Breast
Lung
Testes
Kidney
25
Q

CEA

A

Breast
Gastric
Colorectal
Pancreatic

26
Q

AFP

A

HCC

Yolk Sac tumor

27
Q

BHCG

A

Hydatidiform mole
Choriocarcinoma
GSTT

28
Q

Bombesin

A

Neuroblastoma
Lung
Gastric

29
Q

TRAP

A

Hairy cell leukemia B cell

30
Q

CA 19-9

A

Pancreatic adenocarcinoma

Mucinous adenocarcinoma of the ovary

Pathology 2 (20 decks)

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