Neoplasia Flashcards
Non neoplastic tissue in a foreign location
Choristoma
Non neoplastic overgrowth of disorganized tissue indigenous to a particular site
Hamartoma
Genes involved in the normal growth and repair. Mutations can cause sustained activity of the genes
Proto oncogenes
Mutations can cause unregulated cell proliferation
Two cell hit hypothesis
Tumor suppressor genes
Degree of differentiation of neoplasia
Tumor grade
Degree of localization/spread
Tumor stage
More prognostic value
Cancers in children
ALL > CNS tumors > Burkitt’s lymphoma
Cancers in men
Prostate > lung > colorectal
Cancers in women
Breast > lung > colorectal
Cancer mortality in men
Lung > prostate > colorectal
Cancer mortality in women
Lung > breast > colorectal
Paraneoplastic syndromes
Cushing syndrome
Small cell carcinoma of the lung
Paraneoplastic syndromes
SIADH
Small cell carcinoma of the lung
Paraneoplastic syndromes
Squamous cell carcinoma
Hypercalcemia
Paraneoplastic syndromes
Hypoglycemia
Ovarian carcinoma
Fibrosarcoma
Paraneoplastic syndromes
Carcinoid syndrome
HCC
Bronchial adenoma
Pancreatic carcinoma
Paraneoplastic syndromes
Polycythemia
Gastric and renal carcinoma
Cerebellar hemangioma
Trousseau syndrome
Pancreatic carcinoma
Lambert Eaton syndrome
Lung carcinoma
Red cell aplasia
Thymoma
Nephrotic syndrome
Hodgkin’s lymphoma
Tumor Lysis Syndrome
Hyperkalemia
Hyperphosphatemia
Hyperuricemia
hypocalcemia
Brain Metastases
Lots of Bad Stuff Kill Glia Lung Breast Skin melanoma Kidney renal cell ca GI
Liver Mets
Cancer Sometimes Penetrates Benign Liver Colon Stomach Pancreas Breast Lung
Bone Mets
PurPLe Tinged Barney Loves Tasty Kids Prostate Thyroid follicular Breast Lung Testes Kidney
CEA
Breast
Gastric
Colorectal
Pancreatic
AFP
HCC
Yolk Sac tumor
BHCG
Hydatidiform mole
Choriocarcinoma
GSTT
Bombesin
Neuroblastoma
Lung
Gastric
TRAP
Hairy cell leukemia B cell
CA 19-9
Pancreatic adenocarcinoma
Mucinous adenocarcinoma of the ovary
