Peripheral Circulation and Respiration Flashcards

1
Q

What are the two main functions of the vascular system?

A

distribution and exchange

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2
Q

What makes up the middle layer of the arterial wall and determines the size of the artery?

A

smooth muscle

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3
Q

What makes up the inner layer of the material wall and functions to control flow, protection from clots, and regulation of permeability?

A

endothelial cells

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4
Q

Which layer of the arterial wall contains nerves that contribute to control of contraction?

A

sympathetic vasoconstrictor fiber

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5
Q

The majority of resistance to flow is contributed at the level of the _______.

A

arterioles

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6
Q

What kind of muscle is found in the vascular, bronchi, and gastric sections?

A

non-striated smooth muscle

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7
Q

What are a few differences between VSM cells and striated muscle cells?

A

VSM cells are smaller, only have one nucleus, and a smaller sarcoplasmic reticulum

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8
Q

In stead of “T” tubules what do VSM cells use?

A

Caveolae

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9
Q

In cardiac muscle what provides an electrical link between cells?

A

gap/intermediate junctions

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10
Q

What is the anchor in thin filaments which provides the mechanical connection between cells and contributes to elects recoil?

A

dense bodies

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11
Q

What is the supporting protein which links the dense bodies but does not contribute to the contractile process?

A

intermediate filaments

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12
Q

What is the difference in sarcomere of VSM?

A

fewer in number and not regularly organized as on cardiac and skeletal

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13
Q

What is surrounded by smooth muscle that regulates vascular time and thus resistance to flow?

A

arterioles

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14
Q

What is where exchange of material with surrounding tissues takes place?

A

capillaries

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15
Q

What collects blood flowing out of the capillary bed?

A

venules

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16
Q

What collects interstitial or extravascular fluid and returns it to venous circulation?

A

lymphatics

17
Q

Why are capillaries good exchange vessels?

A

very thin capillary wall which contains holes/pores, blood also flows very slowly

18
Q

Why is blood flow at the capillaries so low?

A

they represent the highest total cross sectional are in circulation

19
Q

What functions to return fluid and plasma protein that have leaked out of the capillaries back to the circulating pool?

A

lymphatic system

20
Q

What covers the surface of the lungs?

A

visceral pleura

21
Q

What lines the walls of the thoracic cavity?

A

parietal pleura

22
Q

What is between the visceral and parietal pleura?

A

pleural cavity

23
Q

What dictates air flow in lungs?

A

changes in pressure in the intrapleural space governed by changes in volume of the thoracic cavity

24
Q

What must be created in the lungs in order to drive the net movement of air from the atmosphere into the lungs?

A

a pressure gradient

25
Q

What does contraction of the diaphragm and external intercostal muscles do?

A

expands volume of thoracic cavity

26
Q

What is volume moving past a given point per unit time?

A

velocity

27
Q

What is layers of flow moving laterally in a distinct way typically in the smaller branched portions?

A

laminar flow

28
Q

What is increased velocity of flow leading to turbulence and increased resistance typically in larger airways, ventricles, aorta, and pulmonary artery?

A

turbulent flow

29
Q

What type of flow occurs in capillaries and erythrocytes?

A

single-file

30
Q

What is the equation for pulse pressure?

A

Systolic pressure - diastolic pressure

31
Q

What is the equation estimated mean arterial pressure?

A

diastolic pressure + pulse pressure/3

32
Q

What causes systolic arterial pressure?

A

during systole the flow of blood from the heart to the arteries exceeds the flow out of the arteries through the arterioles leading to extension/stretching

33
Q

What is diastolic arterial pressure?

A

during diastole the elastic recoil of the arterial walls provides the driving force to propel blood out of the arteries and into vessels

34
Q

What is the pressure due to the presence of colloids, large proteins or other non diffusible materials that remain within the blood plasma, and draws water from the interstitial space back into the capillary?

A

oncotic pressure

35
Q

True or false: smooth muscle can be stimulated to contract without an action potential.

A

True

36
Q

In smooth muscle how can muscle tone be decreased?

A

inhibiting MLCK binding or activating myosin depolarization