perinatal psych Flashcards

1
Q

red flag presentations requiring referral to a specialist perinatal mental health team

A

recent significant change in mental health state or emergence of new symptoms
new thoughts or acts of violent self harm
new and persistent expressions of incompetency as a mother or estrangement from their baby

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2
Q

when to admit to a mother and baby unit

A

rapidly changing mental state
suicidal ideation (particularly of a violent nature)
significant estrangement from the infant
pervasive guilt or hopelessness
beliefs of inadequacy as a mother
evidence of psychosis

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3
Q

good questions to ask when assessing mental health state relating to post natal period

A

do you have new feelings and thoughts which you have never had before, which make you disturbed or anxious?
are you experiencing thoughts of suicide or harming yourself in violent ways?
are you feeling incompetent, as though you can’t cope, or estranged from your baby?
do you feel you are getting worse?

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4
Q

risk factors for mental health issues

A
young/single
domestic issues
lack of support
substance abuse
unplanned/unwnated pregnancy 
pre-existing mental health problem
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5
Q

screening questions to be used in every appointment

A

during the last month have you been bothered by feeling down, depressed or hopeless?
during the last month have you been bothered by having little interest or pleasure in doing things?
is this something you feel you need or want help with?

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6
Q

when to refer to psychiatry

A

psychosis
severe anxiety, depression, suicidal, self-neglect, self harm
symptoms with significant interference with daily functioning
history of bipolar or schizophrenia
history of puerperal psychosis
psychotropic medication
if developed moderate illness in late pregnancy or early post partum
mild-moderate illness but with 1st degree relative with bipolar or puerperal psychosis
previous inpatient admissions to mental health unit

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7
Q

effects of pregnancy on bipolar

A

high rate of relapse postnatally

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8
Q

effects of pregnancy on eating disorders

A

may be some improvement

risks of IUGR, prematurity, hypokalaemia, hyponatraemia, metabolic alkalosis, miscarriage, premature delivery

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9
Q

effects of pregnancy on antenatal depression

A

often relapse if stop meds in pregnancy

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10
Q

management of antenatal depression during pregnancy

A

mild - self help strategies
mild-moderate - GP managed
severe - referral to psych

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11
Q

differential diagnosis of puerperal psychosis

A

episode of bipolar
unipolar depression
schizophrenia
organic brain dysfunction

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12
Q

when does puerperal psychosis present

A

within 2 weeks of delivery

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13
Q

early symptoms of puerperal psychosis

A

sleep disturbance
confusion
irrational ideas

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14
Q

late symptoms of puerperal psychosis

A

mania
delusions
hallucinations
confusion

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15
Q

risk factors for puerperal psychosis

A

bipolar disorder
previous puerperal psychosis
1st degree relative with history

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16
Q

management of puerperal psychosis

A

admission to specialised mother-baby unit

antidepressants, antipsychotics, mood stabilisers, ECT

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17
Q

typical symptoms of postnatal depression

A
tearfullness
irritable 
anxiety
lack of enjoyment and poor sleep
weight loss
can present as concerns re baby
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18
Q

usual onset of post natal depression

A

2-6 weeks

lasts weeks to months

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19
Q

how to differentiate baby blues from postnatal depression

A

baby blues - week 1

depression weeks 2-6

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20
Q

management of postnatal depression

A

mild-moderate - self help, counselling

moderate-severe - psychotherapy and antidepressants, admission?

21
Q

risks to child of untreated depression

A

low birth weight
preterm delivery
adverse childhood outcomes
poor engagement/bonding with child

22
Q

risks of medication during 1st trimester

A

teratogenicity

23
Q

risks of medication in 3rd trimester

A

neonatal withdrawal

24
Q

risks of medication in breast feeding

A

medication passing into breast milk

exposure is less in breast milk than in utero, so if a drug was fine antenatally it should be fine postnatally

25
Q

antidepressants in 1st trimester

A

generally no increase in major malformation or spontaneous abortion

26
Q

antidepressants in 3rd trimester

A

risk of neonatal withdrawal (mild)
increase risk of neonatal persistent pulmonary HTN with SSRIs taken after 20 weeks
increased risk of low birth weight/prematurity

27
Q

antidepressants and breast-feeding

A

all are in breast milk to some extent but no reports of adverse effects on neonatal development

28
Q

paroxetine in the first trimester

A

increased risk of fetal heart defects

29
Q

lowest risk SSRIs in 3rd trimester

A

sertraline or fluoxetine

30
Q

lowest risk TCAs in 3rd trimester

A

imipramine/amitriptyline

lower risk than SSRIs

31
Q

better anti-depressants for breastfeeding

A

sertraline
paroxetine
imipramine

32
Q

BZDs in 1st trimester

A

avoid due to possible increased risk of fetal malformation eg cleft palate

33
Q

BZDs in 3rd trimester

A

avoid due to increased risk of floppy baby syndrome

hypothermia, hypotonia, respiratory depression, withdrawal effects

34
Q

BZDs in breastfeeding

A

avoid regular use - risks of lethargy and weight loss and accumulation of long acting drugs

35
Q

which antipsychotics should be avoided in pregnancy and why

A

clozapine due to risk of agranulocytosis

36
Q

risks of olanzapine in pregnancy

A

increased risk of gestational diabetes and weight gain

37
Q

lithium in 1st trimester

A

increased risk of abnormality

avoid sudden discontinuation

38
Q

lithium in 3rd trimester

A

monitor lithium levels closely due to changes in volume of distribution
lithium toxicity can mimic PET

39
Q

lithium in breastfeeding

A

high quantities in breast milk

AVOID

40
Q

sodium valproate in 1st trimester

A

increased risk of neural tube defects, craniofaical defects and effects on child’s intellectual development
less risk with doses <1000 mg
increased risk of autism

41
Q

sodium valproate in breastfeeding

A

low risk with no evidence of adverse effects in breast feeding

42
Q

carbamazepine in pregnancy

A

increased risk of neural tube defects

facial dysmorphism, fingernail hypoplasia

43
Q

lamotrigine in pregnancy

A

increased risk of oral cleft

risk of Stevens-Johnson syndrome in infancy if breast feeding

44
Q

effects of substance abuse in pregnancy

A

IUGR
stillbirth
SID
pre-term labour

45
Q

effects of alcohol on pregnancy

A

risks of miscarriage
foetal alcohol syndrome (facial deformities, lower IG, neurodevelopment delay, epilepsy, hearing, heart and kidney defects)
withdrawal
risks of wernicke-korsakoff

46
Q

risks of cocaine, amphetamine and ecstasy in pregnancy

A
death via stroke and arrhythmias 
teratogenic (microcephaly, cardiac, GU, limb defects)
pre-eclampsia 
abruption 
IUGR
preterm labour 
miscarriage 
developmental delay
SID
withdrawal
47
Q

effects of opiates in pregnancy

A
maternal deaths 
neonatal withdrawal
IUGR
SIDs
stillbirth
48
Q

effects nicotine in pregnancy

A
miscarriages
abruption 
IUGR
stillbirths 
SIDs