breast anatomy Flashcards

1
Q

how many lobules are there in each breast

A

15-25

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2
Q

what does tubulo-ancinar mean in relation to the breast lobules

A

tubulo- refers to the tubular portion of the terminal duct system
acing refers to the bunch of grapes structure of the gland

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3
Q

what types of tissue are the secretory lobules surrounded by

A

dense fibrous tissue

adipose tissue

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4
Q

what are suspensory ligaments

A

larger condensations of fibrous connective tissue that extend from the dermis of the skin to the deep fascia of the muscle overlying the anterior chest wall

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5
Q

where are the suspensory ligaments most pronounced

A

upper breast

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6
Q

how are the suspensory ligaments of clinical important

A

responsible for the puckered appearance of the breast surface if there is a mass growing in the breast
‘piel de orange’

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7
Q

what is the basic functional secretory unit of the breast

A

terminal duct lobular unit

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8
Q

describe the series of ducts present in the non-lactating breast, starting at the terminal ductule

A

terminal ductule drains into an intralobular collecting duct which leads into the lactiferous duct of that lobe which leads to the nipple

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9
Q

what is the lactiferous sinus

A

an expanded region of the lactiferous duct near the nipple

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10
Q

what type of epithelium lines the larger ducts

A

thin stratified squamous at the nipple
transitions to
stratified cuboidal further in
will then become thinner, maybe one cell thick

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11
Q

what is the purpose of myoepithalial cells in the duct system

A

contract to express milk

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12
Q

describe the difference in the tissue surrounding the lobules and acini

A

lobules: bands of dense fibrocollagenous connective tissue
acini: looser connective tissue to allow for rapid expansion during pregnancy

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13
Q

what type of cells surround the acini

A

myoepithelial

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14
Q

what type of epithelium covers the nipple

A

thin, highly pigmented, keratinised stratified squamous epithelium

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15
Q

the nipple is made up of what type of tissue

A

dense irregular connective tissue mixed with bundles of smooth muscle

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16
Q

how does the proportion of secretory and fibro-fatty tissue change during pregnancy

A

proliferation of secretory tissue

reduction of fibro-fatty tissue

17
Q

what is the composition of human milk

A

88% water
1.5% protein (lactalbumin and casein)
7% carbohydrate (lactose)
3.5% lipid

18
Q

describe apocrine secretion

A

droplets are secreted surrounded by a membrane and carry a small amount of cytoplasm with it

19
Q

which milk components are secreted Bia apocrine secretion

A

lipid

20
Q

describe merocrine secretion

A

vesicles merge with apical membrane and release only their contents into the duct system

21
Q

which milk components are secreted via merocrine secretion

A

proteins

22
Q

what happens to the duct system after menopause

A

secretory cell degenerate leaving only ducts

23
Q

what changes occur in the connective tissue after menopause

A

fewer fibroblasts and reduced collagen and elastic fibres

24
Q

which antibody is secreted in breast milk

A

IgA