Pencillins

Question 1

Pen G Spectrum

Answer 1

Good: syphilis, most streptococci
Mod: enterococci, GP anaerobes

Question 2

Pen G Renal

Answer 2

Decrease maintenance dose in severe

Question 3

Antistaph PCNs

Answer 3

Nafcillin, oxacillin, dicloxacillin

Question 4

Nafcillin, Oxacillin Dosing

Answer 4

IV: 1-3g q4-6h; no renal

Question 5

Aminopenicillins

Answer 5

Amoxicllin, ampicillin

Question 6

Aminopenicillin Spectrum

Answer 6

DOC: E. faecalis
Good: strep
Mod: enteric GNRs, H. flu

Question 7

Amoxicillin Dose

Answer 7

PO: 250-500 mg tid

Question 8

Amoxicillin Renal

Answer 8

10-30: 500 mg q12h, 0-10: q24h

Question 9

Ampicillin Dose

Answer 9

IV/IM: 1-2 g q4-6h, max/day: 12 g

PO: 250-500 mg tid

Question 10

Ampicillin Renal

Answer 10

10-50: q6h, 0-10: q12h

Question 11

Piperacillin/Tazobactam Spectrum

Answer 11

Good: MSSA, Pseudomonas, strept, enterococci, many anaerobes, enteric GNRs

Question 12

Piperacillin/Tazobactam Dosing

Answer 12

IV: 3.375 or 4.5 g q8h over 4 hrs, max/day: 18 g

Question 13

Piperacillin/Tazobactam Renal

Answer 13

20 or less: 2.25 g q8h over 4 hr

Question 14

PCN/BLI Combo

Answer 14

Ampicllin/sulbactam, amoxicillin/clavulante

Question 15

PNC/BLI Combo Spectrum

Answer 15

Good: MSSA, Strept, Enterococci, many anaerobes, enteric GNRS

Question 16

Ampicillin/Sulbactam Dosing

Answer 16

IV/IM: 1.5-3 g q6h, max/day: 12 g

Question 17

Amoxicillin/clavulante

Dosing

Answer 17

PO: 250- 500 mg q8h or 875-2000 mg q12h

Question 18

Amoxicillin/clavulante Renal

Answer 18

10-30: 500mg q12h, 0-10: q24h

Question 19

PCN Interactions

Answer 19

AG - inactivation by PCN in vitro

Question 20

Dicloxacillin Dosing

Answer 20

PO: 125-500 mg q6h, no renal

Question 21

Ampicillin/sulbactam Renal

Answer 21

15-29: 3 g q12h, 0-14: 3 g q24h

Question 22

Antistaph PCN Spectrum

Answer 22

Good: MSSA, Strept